Exercise effects on bone mineral density in men

Mages M, Shojaa M, Kohl M, von Stengel S, Becker C, Gosch M, Jakob F, Kerschan-Schindl K, Kladny B, Klöckner N, Lange U, Middeldorf S, Peters S, Schöne D, Sieber C, Tholen R, Thomasius FE, Uder M, Kemmler W (2021)

Publication Type: Journal article, Review article

Publication year: 2021

Journal

Nutrients MDPI

Book Volume: 13

Article Number: 4244

Journal Issue: 12

DOI: 10.3390/nu13124244

Abstract

In contrast to postmenopausal women, evidence for a favorable effect of exercise on Bone Mineral Density (BMD) is still limited for men. This might be due to the paucity of studies, but also to the great variety of participants and study characteristics that may dilute study results. The aim of the present systematic review and meta-analysis was to evaluate the effect of exercise on BMD changes with rational eligibility criteria. A comprehensive search of six electronic databases up to 15 March 2021 was conducted. Briefly, controlled trials ≥6 months that determined changes in areal BMD in men >18 years old, with no apparent diseases or pharmacological therapy that relevantly affect bone metabolism, were included. BMD changes (standardized mean differences: SMD) of the lumbar spine (LS) and femoral neck (FN) were considered as outcomes. Twelve studies with 16 exercise and 12 control groups were identified. The pooled estimate of random-effect analysis was SMD = 0.38, 95%-CI: 0.14–0.61 and SMD = 0.25, 95%-CI: 0.00–0.49, for LS and FN, respectively. Heterogeneity between the trials was low–moderate. Funnel plots and rank and regression correlation tests indicate evidence for small study publication bias for LS but not FN-BMD. Subgroup analyses that focus on study length, type of exercise and methodologic quality revealed no significant difference between each of the three categories. In summary, we provided further evidence for a low but significant effect of exercise on BMD in men. However, we are currently unable to give even rough exercise recommendations for male cohorts.

Authors with CRIS profile

Mahdieh Shojaa Lehrstuhl für Medizinische Physik und Mikrogewebetechnik Simon von Stengel Lehrstuhl für Medizinische Physik und Mikrogewebetechnik Daniel Schöne Lehrstuhl für Medizinische Physik und Mikrogewebetechnik Cornel Sieber Lehrstuhl für Innere Medizin (Geriatrie) Michael Uder Lehrstuhl für Diagnostische Radiologie Wolfgang Kemmler Lehrstuhl für Medizinische Physik und Mikrogewebetechnik

Involved external institutions

Deutsche Rheuma-Liga Bundesverband e.V. DE Germany (DE) Deutscher Verband für Physiotherapie (ZVK) e. V. DE Germany (DE) Deutsche Gesellschaft für Orthopädie und Unfallchirurgie e.V. (DGOU) DE Germany (DE) Deutsche Gesellschaft für Physikalische und Rehabilitative Medizin (DGPRM) DE Germany (DE) International Musculoskeletal Pain Society IGOST DE Germany (DE) Julius-Maximilians-Universität Würzburg DE Germany (DE) Dachverband Osteologie DVO DE Germany (DE) Österreichische Gesellschaft für Knochen- und Mineralstoffwechsel ÖGKM AT Austria (AT) Klinikum Nürnberg DE Germany (DE) Robert-Bosch-Krankenhaus DE Germany (DE) Deutscher Verband für Gesundheitssport & Sporttherapie (DVGS) e.V. DE Germany (DE) Hochschule Furtwangen DE Germany (DE)

How to cite

APA:

Mages, M., Shojaa, M., Kohl, M., von Stengel, S., Becker, C., Gosch, M.,... Kemmler, W. (2021). Exercise effects on bone mineral density in men. Nutrients, 13(12). https://doi.org/10.3390/nu13124244

MLA:

Mages, Michelle, et al. "Exercise effects on bone mineral density in men." Nutrients 13.12 (2021).

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