Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer Long-term Results of the CAO/ARO/AIO-12 Randomized Clinical Trial

Fokas E, Schlenska-Lange A, Polat B, Klautke G, Grabenbauer GG, Fietkau R, Kuhnt T, Staib L, Brunner T, Grosu AL, Kirste S, Jacobasch L, Allgaeuer M, Flentje M, Germer CT, Grützmann R, Hildebrandt G, Schwarzbach M, Bechstein WO, Suelberg H, Friede T, Gaedcke J, Ghadimi M, Hofheinz RD, Roedel C (2021)

Publication Type: Journal article

Publication year: 2021

Journal

JAMA Oncology American Medical Association (AMA)

DOI: 10.1001/jamaoncol.2021.5445

Abstract

IMPORTANCE Total neoadjuvant therapy has been increasingly adopted for multimodal rectal cancer treatment. The optimal sequence of chemoradiotherapy (CRT) and chemotherapy needs to be established.

Authors with CRIS profile

Rainer Fietkau Lehrstuhl für Strahlentherapie Robert Grützmann Lehrstuhl für Allgemein- und Viszeralchirurgie

Involved external institutions

Otto-von-Guericke-Universität Magdeburg DE Germany (DE) Universitätsklinikum Göttingen DE Germany (DE) Universität Rostock DE Germany (DE) Albert-Ludwigs-Universität Freiburg DE Germany (DE) Poliklinik Chemnitz DE Germany (DE) Universitätsklinikum Mannheim DE Germany (DE) Krankenhaus Barmherzige Brüder DE Germany (DE) Julius-Maximilians-Universität Würzburg DE Germany (DE) Goethe-Universität Frankfurt am Main DE Germany (DE) Universität Leipzig DE Germany (DE) Universitätsklinikum Frankfurt am Main (KGU) DE Germany (DE) DiaCura - Praxis für Radiologische Diagnostik, Strahlentherapie und Radioonkologie DE Germany (DE) Städtische Kliniken Esslingen DE Germany (DE) X-act Cologne Clinical Research GmbH DE Germany (DE)

How to cite

APA:

Fokas, E., Schlenska-Lange, A., Polat, B., Klautke, G., Grabenbauer, G.G., Fietkau, R.,... Roedel, C. (2021). Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer Long-term Results of the CAO/ARO/AIO-12 Randomized Clinical Trial. JAMA Oncology. https://doi.org/10.1001/jamaoncol.2021.5445

MLA:

Fokas, Emmanouil, et al. "Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer Long-term Results of the CAO/ARO/AIO-12 Randomized Clinical Trial." JAMA Oncology (2021).

BibTeX: Download