Stumpf H, Nowakowski P, Eggeling C, Maciolek A, Smith AS (2021)
Publication Type: Journal article
Publication year: 2021
Book Volume: 3
Journal Issue: 4
DOI: 10.1103/PhysRevResearch.3.L042013
Specific lipid environments are necessary for the establishment of protein signaling platforms in membranes, yet their origin has been highly debated. We present a continuum, exactly solvable model of protein induced local demixing of lipid membranes. The coupling between a local composition and a local thickness of the membrane induces lipid domains around inclusions with hydrophobic mismatch, even for temperatures above the miscibility critical point of the membrane. The model qualitatively explains the experimentally observed formation of lipid domains induced by anchoring of reconstituted actin in flat supported lipid bilayers.
APA:
Stumpf, H., Nowakowski, P., Eggeling, C., Maciolek, A., & Smith, A.-S. (2021). Protein induced lipid demixing in homogeneous membranes. Physical Review Research, 3(4). https://doi.org/10.1103/PhysRevResearch.3.L042013
MLA:
Stumpf, Henning, et al. "Protein induced lipid demixing in homogeneous membranes." Physical Review Research 3.4 (2021).
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