Autoimmune glomerulonephritis in a multiple sclerosis patient after cladribine treatment

Schoenfelder K, Schuh H, Pfister F, Kraemer J, Eisenberger U, Skuljec J, Hackert J, Ruck T, Pfeuffer S, Fleischer M, Gaeckler A, Hagenacker T, Kribben A, Meuth SG, Kleinschnitz C, Pul R (2021)


Publication Type: Journal article

Publication year: 2021

Journal

DOI: 10.1177/13524585211022719

Abstract

Background: Oral cladribine is an approved disease-modifying drug for the treatment of relapsing multiple sclerosis. In controlled clinical trials as well as in post marketing safety assessments, autoimmune conditions have not yet been reported as a specific side effect of cladribine. Objective and Results: Here, we report a case of anti-glomerular basement membrane antibody-mediated glomerulonephritis that occurred shortly after the fourth cladribine treatment cycle. Conclusion: Neurologists should be attentive to the development of secondary autoimmunity in cladribine-treated patients.

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APA:

Schoenfelder, K., Schuh, H., Pfister, F., Kraemer, J., Eisenberger, U., Skuljec, J.,... Pul, R. (2021). Autoimmune glomerulonephritis in a multiple sclerosis patient after cladribine treatment. Multiple sclerosis journal. https://doi.org/10.1177/13524585211022719

MLA:

Schoenfelder, Kristina, et al. "Autoimmune glomerulonephritis in a multiple sclerosis patient after cladribine treatment." Multiple sclerosis journal (2021).

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