Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled trial

Azizi M, Sanghvi K, Saxena M, Gosse P, Reilly JP, Levy T, Rump LC, Persu A, Basile J, Bloch MJ, Daemen J, Lobo MD, Mahfoud F, Schmieder R, Sharp ASP, Weber MA, Sapoval M, Fong P, Pathak A, Lantelme P, Hsi D, Bangalore S, Witkowski A, Weil J, Kably B, Barman NC, Reeve-Stoffer H, Coleman L, Mcclure CK, Kirtane AJ (2021)

Publication Type: Journal article

Publication year: 2021

Journal

Book Volume: 397

Pages Range: 2476-2486

Journal Issue: 10293

DOI: 10.1016/S0140-6736(21)00788-1

Abstract

Background Endovascular renal denervation reduces blood pressure in patients with mild-to-moderate hypertension, but its efficacy in patients with true resistant hypertension has not been shown. We aimed to assess the efficacy and safety of endovascular ultrasound renal denervation in patients with hypertension resistant to three or more antihypertensive medications.

Authors with CRIS profile

Involved external institutions

University of Paris 4 - Paris-Sorbonne / Université paris IV Paris-Sorbonne France (FR) Deborah Heart and Lung Center United States (USA) (US) Queen Mary University of London United Kingdom (GB) Centre Hospitalier Universitaire de Bordeaux / CHU Bordeaux France (FR) Ochsner Health System United States (USA) (US) Royal Bournemouth Hospital United Kingdom (GB) Universitätsklinikum Düsseldorf Germany (DE) Cliniques universitaires Saint-Luc (CHU St-Luc) Belgium (BE) Medical University of South Carolina (MUSC) United States (USA) (US) University of Nevada Las Vegas United States (USA) (US) Erasmus University Medical Center (MC) Netherlands (NL) Universitätsklinikum des Saarlandes (UKS) Germany (DE) Cardiff and Vale University Health Board United Kingdom (GB) SUNY Downstate Medical Center United States (USA) (US) Vanderbilt University United States (USA) (US) Centre Hospitalier Princesse Grace Monaco (MC) Croix-Rousse hospital / Hôpital de la Croix-Rousse France (FR) Stamford Hospital United States (USA) (US) New York University (NYU) United States (USA) (US) Institute of Cardiology in Warsaw Poland (PL) Sana Kliniken Lübeck GmbH Germany (DE) ReCor Medical Inc. United States (USA) (US) North American Science Associates (NAMSA) United States (USA) (US) Columbia University United States (USA) (US)

How to cite

APA:

Azizi, M., Sanghvi, K., Saxena, M., Gosse, P., Reilly, J.P., Levy, T.,... Kirtane, A.J. (2021). Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled trial. The Lancet, 397(10293), 2476-2486. https://doi.org/10.1016/S0140-6736(21)00788-1

MLA:

Azizi, Michel, et al. "Ultrasound renal denervation for hypertension resistant to a triple medication pill (RADIANCE-HTN TRIO): a randomised, multicentre, single-blind, sham-controlled trial." The Lancet 397.10293 (2021): 2476-2486.

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