Blood circuit reconstruction in an abdominal mouse heart transplantation model

Yin D, Fu J, Allabauer I, Witzke O, Rong S, Hörning A (2021)

Publication Type: Journal article

Publication year: 2021

Journal

Journal of Visualized Experiments MYJoVE Corporation

Book Volume: 2021

Article Number: e62007

Journal Issue: 172

DOI: 10.3791/62007

Abstract

The surgical technique of heterotopic abdominal heart transplantation in mice is a standard model for research in transplantation immunology. Here, the established technique for a modified blood circuit reconstruction in a heterotopic abdominal heart transplantation model is presented. This method uses the intrathoracic inferior vena cava (IIVC) instead of the pulmonary artery of the donor heart for the anastomosis to the inferior vena cava of the recipient. It is facilitating and improving success rates for abdominal heart transplantation in mice.

Authors with CRIS profile

Decheng Yin Lehrstuhl für Kinder- und Jugendmedizin André Hörning Department of Paediatrics and Adolescent Medicine

Involved external institutions

Universitätsklinikum Essen DE Germany (DE) Medizinische Hochschule Hannover (MHH) / Hannover Medical School DE Germany (DE)

How to cite

APA:

Yin, D., Fu, J., Allabauer, I., Witzke, O., Rong, S., & Hörning, A. (2021). Blood circuit reconstruction in an abdominal mouse heart transplantation model. Journal of Visualized Experiments, 2021(172). https://doi.org/10.3791/62007

MLA:

Yin, Decheng, et al. "Blood circuit reconstruction in an abdominal mouse heart transplantation model." Journal of Visualized Experiments 2021.172 (2021).

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