Lewczuk P (2021)
Publication Type: Book chapter / Article in edited volumes
Publication year: 2021
Publisher: Humana Press Inc.
Edited Volumes: Neuromethods
Series: Neuromethods
Book Volume: 168
Pages Range: 17-27
DOI: 10.1007/978-1-0716-1319-1_2
CSF concentrations of albumin and immunoglobulins (IgG, IgA, and IgM) are contemporary analyzed by fully automated, particle-enhanced turbidimetry or nephelometry. Turbidimetry measures decrease of the intensity of light passing through a solution (a CSF sample) due to its scattering on the particles suspended in this sample. Nephelometry applies a similar principle, but with a light detector placed at an angel to the source. This allows measurement of the intensity of the light reflected on the particles suspended in a sample. Diagnostically relevant are concentrations of albumin, IgG, IgA, and IgM. To normalize their CSF concentrations for the concentrations in the blood, the results are expressed as CSF/serum concentrations quotients (i.e., Q
APA:
Lewczuk, P. (2021). Nephelometry and Turbidimetry: Methods to Quantify Albumin and Immunoglobulins Concentrations in Clinical Neurochemistry. In Neuromethods. (pp. 17-27). Humana Press Inc..
MLA:
Lewczuk, Piotr. "Nephelometry and Turbidimetry: Methods to Quantify Albumin and Immunoglobulins Concentrations in Clinical Neurochemistry." Neuromethods. Humana Press Inc., 2021. 17-27.
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