Azizov V, Zaiss M (2021)
Publication Type: Journal article, Review article
Publication year: 2021
Book Volume: 13
Article Number: 1324
Journal Issue: 4
DOI: 10.3390/nu13041324
Benefits and harms of different components of human diet have been known for hundreds of years. Alcohol is one the highest consumed, abused, and addictive substances worldwide. Con-sequences of alcohol abuse are increased risks for diseases of the cardiovascular system, liver, and nervous system, as well as reduced immune system function. Paradoxically, alcohol has also been a consistent protective factor against the development of autoimmune diseases such as type 1 diabetes, multiple sclerosis, systemic lupus erythematosus, and rheumatoid arthritis (RA). Here, we focused on summarizing current findings on the effects of alcohol, as well as of its’ metabolites, acetaldehyde and acetate, on the immune system and RA. Heavy or moderate alcohol consumption can affect intestinal barrier integrity, as well as the microbiome, possibly contributing to RA. Additionally, systemic increase in acetate negatively affects humoral immune response, diminishing T
APA:
Azizov, V., & Zaiss, M. (2021). Alcohol consumption in rheumatoid arthritis: A path through the immune system. Nutrients, 13(4). https://doi.org/10.3390/nu13041324
MLA:
Azizov, Vugar, and Mario Zaiss. "Alcohol consumption in rheumatoid arthritis: A path through the immune system." Nutrients 13.4 (2021).
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