Contrast-enhanced ultrasound of the pediatric brain
Hwang M, Barnewolt CE, Jüngert JM, Prada F, Sridharan A, Didier RA (2021)
Publication Type: Journal article, Review article
Publication year: 2021
Journal
DOI: 10.1007/s00247-021-04974-4
Abstract
Brain contrast-enhanced ultrasound (CEUS) is an emerging application that can complement gray-scale US and yield additional insights into cerebral flow dynamics. CEUS uses intravenous injection of ultrasound contrast agents (UCAs) to highlight tissue perfusion and thus more clearly delineate cerebral pathologies including stroke, hypoxic–ischemic injury and focal lesions such as tumors and vascular malformations. It can be applied not only in infants with open fontanelles but also in older children and adults via a transtemporal window or surgically created acoustic window. Advancements in CEUS technology and post-processing methods for quantitative analysis of UCA kinetics further elucidate cerebral microcirculation. In this review article we discuss the CEUS examination protocol for brain imaging in children, current clinical applications and future directions for research and clinical uses of brain CEUS.
Involved external institutions
Children's Hospital of Philadelphia
United States (USA) (US)
Harvard University
United States (USA) (US)
Foundation of the Carlo Besta Neurological Institute (IRCCS)
Italy (IT)
United States (USA) (US)
Harvard University
United States (USA) (US)
Foundation of the Carlo Besta Neurological Institute (IRCCS)
Italy (IT)
How to cite
APA:
Hwang, M., Barnewolt, C.E., Jüngert, J.M., Prada, F., Sridharan, A., & Didier, R.A. (2021). Contrast-enhanced ultrasound of the pediatric brain. Pediatric Radiology. https://doi.org/10.1007/s00247-021-04974-4
MLA:
Hwang, Misun, et al. "Contrast-enhanced ultrasound of the pediatric brain." Pediatric Radiology (2021).
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