Clinical routine acquisition protocol for 3D relaxation-compensated APT and rNOE CEST-MRI of the human brain at 3T

Goerke S, Breitling J, Korzowski A, Paech D, Zaiß M, Schlemmer HP, Ladd ME, Bachert P (2021)

Publication Type: Journal article

Publication year: 2021

Journal

Magnetic Resonance in Medicine Wiley

DOI: 10.1002/mrm.28699

Abstract

Purpose The value of relaxation-compensated amide proton transfer (APT) and relayed nuclear Overhauser effect (rNOE) chemical exchange saturation transfer (CEST)-MRI has already been demonstrated in various neuro-oncological clinical applications. Recently, we translated the approach from 7T to a clinically relevant magnetic field strength of 3T. However, the overall acquisition time was still too long for a broad application in the clinical setting. The aim of this study was to establish a shorter acquisition protocol whilst maintaining the contrast behavior and reproducibility.

Authors with CRIS profile

Moritz Zaiß Professur für Multimodale Bildgebung in der klinischen Forschung

Involved external institutions

Deutsches Krebsforschungszentrum (DKFZ) DE Germany (DE)

How to cite

APA:

Goerke, S., Breitling, J., Korzowski, A., Paech, D., Zaiß, M., Schlemmer, H.-P.,... Bachert, P. (2021). Clinical routine acquisition protocol for 3D relaxation-compensated APT and rNOE CEST-MRI of the human brain at 3T. Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.28699

MLA:

Goerke, Steffen, et al. "Clinical routine acquisition protocol for 3D relaxation-compensated APT and rNOE CEST-MRI of the human brain at 3T." Magnetic Resonance in Medicine (2021).

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