Clinical feasibility of a high-resolution thermal monitoring sheet for superficial hyperthermia in breast cancer patients
Bakker A, Zweije R, Kok HP, Kolff MW, Desiree van den Bongard HJ, Schmidt M, van Tienhoven G, Crezee H (2020)
Publication Type: Journal article
Publication year: 2020
Journal
Book Volume: 12
Pages Range: 1-18
Article Number: 3644
Journal Issue: 12
Abstract
Background: Accurate monitoring of skin surface temperatures is necessary to ensure treatment quality during superficial hyperthermia. A high-resolution thermal monitoring sheet (TMS) was developed to monitor the skin surface temperature distribution. The influence of the TMS on applicator performance was investigated, feasibility and ability to reliably monitor the temperature distribution were evaluated in a clinical study. Methods: Phantom experiments were performed to determine the influence of the TMS on power deposition patterns, applicator efficiency, and heat transfer of the water bolus for 434 and 915 MHz applicators. Clinical feasibility was evaluated in 10 women with locoregional recurrent breast cancer. Skin surface temperatures during consecutive treatments were monitored alternatingly with either standard Amsterdam UMC thermometry or TMS. Treatments were compared using (generalized) linear mixed models. Results: The TMS did not significantly affect power deposition patterns and applicator efficiency (1–2%), the reduced heat transfer of the water boluses (51–56%) could be compensated by adjusting the water bolus flow. Skin surface temperatures were monitored reliably, and no alteration of thermal toxicity was observed compared to standard Amsterdam UMC thermometry. Conclusion: Clinical application of the TMS is feasible. Power deposition patterns and applicator efficiency were not affected. Surface temperatures were monitored reliably.
Involved external institutions
Netherlands (NL)How to cite
APA:
Bakker, A., Zweije, R., Kok, H.P., Kolff, M.W., Desiree van den Bongard, H.J., Schmidt, M.,... Crezee, H. (2020). Clinical feasibility of a high-resolution thermal monitoring sheet for superficial hyperthermia in breast cancer patients. Cancers, 12(12), 1-18. https://dx.doi.org/10.3390/cancers12123644
MLA:
Bakker, Akke, et al. "Clinical feasibility of a high-resolution thermal monitoring sheet for superficial hyperthermia in breast cancer patients." Cancers 12.12 (2020): 1-18.
BibTeX: Download