Post-Stroke Cardiovascular Complications and Neurogenic Cardiac Injury: JACC State-of-the-Art Review

Sposato LA, Hilz MJ, Aspberg S, Murthy SB, Bahit MC, Hsieh CY, Sheppard MN, Scheitz JF (2020)


Publication Type: Journal article, Review article

Publication year: 2020

Journal

Book Volume: 76

Pages Range: 2768-2785

Journal Issue: 23

DOI: 10.1016/j.jacc.2020.10.009

Abstract

Over 1.5 million deaths worldwide are caused by neurocardiogenic syndromes. Furthermore, the consequences of deleterious brain-heart interactions are not limited to fatal complications. Cardiac arrhythmias, heart failure, and nonfatal coronary syndromes are also common. The brain-heart axis is implicated in post-stroke cardiovascular complications known as the stroke-heart syndrome, sudden cardiac death, and Takotsubo syndrome, among other neurocardiogenic syndromes. Multiple pathophysiological mechanisms with the potential to be targeted with novel therapies have been identified in the last decade. In the present state-of-the-art review, we describe recent advances in the understanding of anatomical and functional aspects of the brain-heart axis, cardiovascular complications after stroke, and a comprehensive pathophysiological model of stroke-induced cardiac injury.

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How to cite

APA:

Sposato, L.A., Hilz, M.-J., Aspberg, S., Murthy, S.B., Bahit, M.C., Hsieh, C.Y.,... Scheitz, J.F. (2020). Post-Stroke Cardiovascular Complications and Neurogenic Cardiac Injury: JACC State-of-the-Art Review. Journal of the American College of Cardiology, 76(23), 2768-2785. https://doi.org/10.1016/j.jacc.2020.10.009

MLA:

Sposato, Luciano A., et al. "Post-Stroke Cardiovascular Complications and Neurogenic Cardiac Injury: JACC State-of-the-Art Review." Journal of the American College of Cardiology 76.23 (2020): 2768-2785.

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