MUC4 is a valuable marker for distinguishing secretory carcinoma of the salivary glands from its mimics

Taverna C, Baneckova M, Lorenzon M, Palomba A, Franchi A, Skalova A, Agaimy A (2020)

Publication Type: Journal article

Publication year: 2020

Journal

Histopathology Wiley

DOI: 10.1111/his.14251

Abstract

Aims Secretory carcinoma (SC) (synonym: mammary analogue secretory carcinoma) is a low-grade salivary gland tumour that occurs in both major and minor salivary glands. SC is known for its wide morphological, architectural and immunohistochemical spectrum, which overlaps with those of several salivary gland neoplasms, including acinic cell carcinoma (AciCC) and intercalated duct-type intraductal carcinoma (IDC) in major salivary glands, and polymorphous adenocarcinoma (PAC) in minor salivary glands. These tumours share with SC some morphological features and SOX10 immunoreactivity; also, with the exception of AciCC, they all coexpress S100 and mammaglobin.

Authors with CRIS profile

Abbas Agaimy Lehrstuhl für Allgemeine Pathologie und Pathologische Anatomie

Involved external institutions

Careggi University Hospital / Azienda Ospedaliero Universitaria Careggi IT Italy (IT) University of Pisa / Università di Pisa (UniPi) IT Italy (IT) Univerzita Karlova v Praze / Charles University in Prague CZ Czech Republic (CZ) Lawrence Berkeley National Laboratory (LBNL) US United States (USA) (US)

How to cite

APA:

Taverna, C., Baneckova, M., Lorenzon, M., Palomba, A., Franchi, A., Skalova, A., & Agaimy, A. (2020). MUC4 is a valuable marker for distinguishing secretory carcinoma of the salivary glands from its mimics. Histopathology. https://doi.org/10.1111/his.14251

MLA:

Taverna, Cecilia, et al. "MUC4 is a valuable marker for distinguishing secretory carcinoma of the salivary glands from its mimics." Histopathology (2020).

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