Kreß A, Grassmann R, Fleckenstein B (2011)
Publication Type: Journal article, Review article
Publication year: 2011
Book Volume: 3
Pages Range: 1439-1459
Journal Issue: 8
DOI: 10.3390/v3081439
The phenotype of HTLV-1-transformed CD4 + T lymphocytes largely depends on defined viral effector molecules such as the viral oncoprotein Tax. In this review, we exemplify the expression pattern of characteristic lineage markers, costimulatory receptors and ligands of the tumor necrosis factor superfamily, cytokine receptors, and adhesion molecules on HTLV-1-transformed cells. These molecules may provide survival signals for the transformed cells. Expression of characteristic surface markers might therefore contribute to persistence of HTLV-1-transformed lymphocytes and to the development of HTLV-1-associated disease. © 2011 by the authors; licensee MDPI, Basel, Switzerland.
APA:
Kreß, A., Grassmann, R., & Fleckenstein, B. (2011). Cell surface markers in HTLV-1 pathogenesis. Viruses, 3(8), 1439-1459. https://dx.doi.org/10.3390/v3081439
MLA:
Kreß, Andrea, Ralph Grassmann, and Bernhard Fleckenstein. "Cell surface markers in HTLV-1 pathogenesis." Viruses 3.8 (2011): 1439-1459.
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