In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors

Zeis P, Lian M, Fan X, Herman JS, Hernandez DC, Gentek R, Elias S, Symowski C, Knoepper K, Peltokangas N, Friedrich C, Doucet-Ladeveze R, Kabat AM, Locksley RM, Vöhringer D, Bajenoff M, Rudensky AY, Romagnani C, Gruen D, Gasteiger G (2020)

Publication Type: Journal article

Publication year: 2020

Journal

Immunity Elsevier

Book Volume: 53

Pages Range: 775-792.e9

Journal Issue: 4

DOI: 10.1016/j.immuni.2020.09.002

Abstract

To investigate how innate lymphoid cells (ILCs) are locally maintained, Zeis et al. generated a single-cell atlas of lung ILCs and tracked Il18r1+ progenitor and effector ILC2s. Their work identifies tissue-resident and circulating ILC progenitors and highlights in situ differentiation and tissue adaptation as a mechanism of ILC renewal and phenotypic diversification.

Authors with CRIS profile

Cornelia Symowski Department of Infection Biology David Vöhringer Professur für Infektionsabwehr und Toleranz

Involved external institutions

Aix-Marseille University / Aix-Marseille Université FR France (FR) University of California San Francisco (UCSF) US United States (USA) (US) Memorial Sloan Kettering Cancer Center US United States (USA) (US) Max-Planck-Institut für Immunbiologie und Epigenetik (MPI-IE) / Max Planck Institute of Immunobiology and Epigenetics DE Germany (DE) Deutsches Rheuma-Forschungszentrum (DRFZ) DE Germany (DE) Julius-Maximilians-Universität Würzburg DE Germany (DE)

How to cite

APA:

Zeis, P., Lian, M., Fan, X., Herman, J.S., Hernandez, D.C., Gentek, R.,... Gasteiger, G. (2020). In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors. Immunity, 53(4), 775-792.e9. https://doi.org/10.1016/j.immuni.2020.09.002

MLA:

Zeis, Patrice, et al. "In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors." Immunity 53.4 (2020): 775-792.e9.

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