Quantitative Imaging in Muscle Diseases with Focus on Non-proton MRI and Other Advanced MRI Techniques

Weber MA, Nagel AM, Kan HE, Wattjes MP (2020)

Publication Type: Journal article

Publication year: 2020

Journal

Seminars in Musculoskeletal Radiology Thieme Publishing / Georg Thieme Verlag

Book Volume: 24

Pages Range: 402-412

Journal Issue: 04

DOI: 10.1055/s-0040-1712955

Abstract

The role of neuromuscular imaging in the diagnosis of inherited and acquired muscle diseases has gained clinical relevance. In particular, magnetic resonance imaging (MRI), especially whole-body applications, is increasingly being used for the diagnosis and monitoring of disease progression. In addition, they are considered as a powerful outcome measure in clinical trials. Because many muscle diseases have a distinct muscle involvement pattern, whole-body imaging can be of diagnostic value by identifying this pattern and thus narrowing the differential diagnosis and supporting the clinical diagnosis. In addition, more advanced MRI applications including non-proton MRI, diffusion tensor imaging, perfusion MRI, T2 mapping, and magnetic resonance spectroscopy provide deeper insights into muscle pathophysiology beyond the mere detection of fatty degeneration and/or muscle edema. In this review article, we present and discuss recent data on these quantitative MRI techniques in muscle diseases, with a particular focus on non-proton imaging techniques.

Authors with CRIS profile

Armin Michael Nagel Professur für metabolische und funktionelle MR-Bildgebung

Involved external institutions

Universitätsmedizin Rostock DE Germany (DE) Medizinische Hochschule Hannover (MHH) / Hannover Medical School DE Germany (DE) Leiden University NL Netherlands (NL)

How to cite

APA:

Weber, M.-A., Nagel, A.M., Kan, H.E., & Wattjes, M.P. (2020). Quantitative Imaging in Muscle Diseases with Focus on Non-proton MRI and Other Advanced MRI Techniques. Seminars in Musculoskeletal Radiology, 24(04), 402-412. https://doi.org/10.1055/s-0040-1712955

MLA:

Weber, Marc-Andre, et al. "Quantitative Imaging in Muscle Diseases with Focus on Non-proton MRI and Other Advanced MRI Techniques." Seminars in Musculoskeletal Radiology 24.04 (2020): 402-412.

BibTeX: Download