Nanoscale departures: Excess lipid leaving the surface during supported lipid bilayer formation
Zhu L, Gregurec D, Reviakine I (2013)
Publication Type: Journal article
Publication year: 2013
Journal
Book Volume: 29
Pages Range: 15283-15292
Journal Issue: 49
DOI: 10.1021/la401354j
Abstract
The behavior of small liposomes on surfaces of inorganic oxides remains enigmatic. Under appropriate conditions it results in the formation of supported lipid bilayers (SLBs). During this process, some lipids leave the surface (desorb). We were able to visualize this by a combination of time-resolved fluorescence microscopy and fluorescence recovery after photobleaching studies. Our observations also allowed us to analyze the kinetics of bilayer patch growth during the late stages of SLB formation. We found that it entails a balance between desorption of excess lipids and further adsorption of liposomes from solution. These studies were performed with liposomes containing zwitterionic phospholipids (dioleoylphosphatidylcholine alone or a mixture of dioleoylphosphatidylcholine, dipalmitoylphosphatidylcholine, and cholesterol) on TiO2 in the presence of Ca2+ but in the absence of other salts. © 2013 American Chemical Society.
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APA:
Zhu, L., Gregurec, D., & Reviakine, I. (2013). Nanoscale departures: Excess lipid leaving the surface during supported lipid bilayer formation. Langmuir, 29(49), 15283-15292. https://doi.org/10.1021/la401354j
MLA:
Zhu, Ling, Danijela Gregurec, and Ilya Reviakine. "Nanoscale departures: Excess lipid leaving the surface during supported lipid bilayer formation." Langmuir 29.49 (2013): 15283-15292.
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