Neuroinflammation in the pathogenesis of early life epileptic encephalopathies
Salar S, Galanopoulou AS (2018)
Publication Type: Book chapter / Article in edited volumes
Publication year: 2018
Publisher: Elsevier Inc.
Edited Volumes: Acute Encephalopathy and Encephalitis in Infancy and Its Related Disorders
Pages Range: 33-44
DOI: 10.1016/B978-0-323-53088-0.00005-1
Abstract
Epileptic encephalopathies consist of a spectrum of disorders commonly seen early in life leading to cognitive impairment and behavioral abnormalities, thought to be largely due to the intense epileptic activity. To date, genetic, structural/metabolic, inflammatory, and functional/network changes are identified as underlying etiologies of these disorders. Here we will focus on the role of neuroinflammation as a potential contributor to the pathogenesis and treatment of some of these disorders, based on clinical and preclinical studies. Namely, we will focus on infantile spasms/West syndrome, Lennox-Gastaut syndrome, Landau-Kleffner syndrome, continuous spike waves in sleep syndrome, and Dravet syndrome.
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APA:
Salar, S., & Galanopoulou, A.S. (2018). Neuroinflammation in the pathogenesis of early life epileptic encephalopathies. In Hideo Yamanouchi, Solomon L. Moshé, Akihisa Okumura (Eds.), Acute Encephalopathy and Encephalitis in Infancy and Its Related Disorders. (pp. 33-44). Elsevier Inc..
MLA:
Salar, Seda, and Aristea S. Galanopoulou. "Neuroinflammation in the pathogenesis of early life epileptic encephalopathies." Acute Encephalopathy and Encephalitis in Infancy and Its Related Disorders. Ed. Hideo Yamanouchi, Solomon L. Moshé, Akihisa Okumura, Elsevier Inc., 2018. 33-44.
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