Strong hypoxia reduces leptin synthesis in purified primary human trophoblasts

Nuesken E, Herrmann Y, Wohlfarth M, Goecke TW, Appel S, Schneider H, Doetsch J, Nuesken KD (2015)

Publication Type: Journal article

Publication year: 2015

Journal

Placenta Elsevier

Book Volume: 36

Pages Range: 427-432

Journal Issue: 4

DOI: 10.1016/j.placenta.2015.01.191

Abstract

Introduction Oxygen availability severely affects placental function. During placental hypoxia, stabilization of hypoxia inducible factors (HIFs) affects transcription, and leptin gene expression concomitantly increases in vivo and in vitro. However, a causal relationship is uncertain.

Authors with CRIS profile

Holm Schneider Professur für Kinderheilkunde/Experimentelle Perinatalmedizin

Involved external institutions

Universität zu Köln DE Germany (DE)

How to cite

APA:

Nuesken, E., Herrmann, Y., Wohlfarth, M., Goecke, T.W., Appel, S., Schneider, H.,... Nuesken, K.D. (2015). Strong hypoxia reduces leptin synthesis in purified primary human trophoblasts. Placenta, 36(4), 427-432. https://doi.org/10.1016/j.placenta.2015.01.191

MLA:

Nuesken, E., et al. "Strong hypoxia reduces leptin synthesis in purified primary human trophoblasts." Placenta 36.4 (2015): 427-432.

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