Choriocapillaris thickness and density in axially elongated eyes
Panda-Jonas S, Holbach L, Jonas JB (2020)
Publication Type: Journal article
Publication year: 2020
Journal
DOI: 10.1111/aos.14486
Abstract
PURPOSE: Axial myopia is characterized by a thinning of the choroid. We examined whether the myopic choroidal thinning also includes a thinning of the choriocapillaris. METHODS: Using light microscopy, we measured thickness and density of the choriocapillaris at the posterior pole, posterior pole-equator midpoint (PPEMP), equator and close to the ora serrata on histological sections of 58 enucleated human globes (mean age: 62.4 ± 17.8 years; range: 24-88 years; mean axial length: 27.8 ± 4.0 mm; range: 22.0-37.0 mm). RESULTS: Choriocapillaris thickness decreased (p < 0.001) from the posterior pole (median: 3.9 µm; interquartile range (IQR): 3.3-6.0) to the equator (median: 2.7 µm; IQR: 1.5, 4.2). It was not significantly associated with axial length, neither at the posterior pole (p = 0.25), the PPEMP (p = 0.81), equator (p = 0.80) or ora serrata (p = 0.50). Mean choriocapillaris density decreased from the posterior pole to the equator (198 µm/300 µm; IQR: 152/300, 246/300 versus 156 µm/300 µm; IQR: 72/300, 216/300; p < 0.001). Choriocapillaris density was not significantly associated with axial length (posterior pole: p = 0.07; PPEMP: p = 0.33; equator: p = 0.22; ora serrata: p = 0.36). CONCLUSIONS: The choriocapillaris thickness and density, decreasing from the posterior pole to the fundus periphery, were not significantly associated with axial length. These findings may be of interest for the understanding of high myopia and pathologic myopia.
Involved external institutions
Germany (DE)How to cite
APA:
Panda-Jonas, S., Holbach, L., & Jonas, J.B. (2020). Choriocapillaris thickness and density in axially elongated eyes. Acta Ophthalmologica. https://dx.doi.org/10.1111/aos.14486
MLA:
Panda-Jonas, Songhomitra, Leonard Holbach, and Jost B. Jonas. "Choriocapillaris thickness and density in axially elongated eyes." Acta Ophthalmologica (2020).
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