Treatment Motivations and Expectations in Patients with Actinic Keratosis: A German-Wide Multicenter, Cross-Sectional Trial
Steeb T, Wessely A, Von Bubnoff D, Dirschka T, Drexler K, Falkenberg C, Hassel JC, Hayani K, Huening S, Kaehler KC, Karrer S, Krammer C, Leiter U, Lill D, Marsela E, Meiwes A, Nashan D, Nasifoglu S, Schmitz L, Sirokay J, Thiem A, Utikal J, Zink A, Berking C, Heppt M (2020)
Publication Type: Journal article
Publication year: 2020
Journal
Book Volume: 9
Journal Issue: 5
DOI: 10.3390/jcm9051438
Abstract
Patient-centered motives and expectations of the treatment of actinic keratoses (AK) have received little attention until now. Hence, we aimed to profile and cluster treatment motivations and expectations among patients with AK in a nationwide multicenter, cross-sectional study including patients from 14 German skin cancer centers. Patients were asked to complete a self-administered questionnaire. Treatment motives and expectations towards AK management were measured on a visual analogue scale from 1-10. Specific patient profiles were investigated with subgroup and correlation analysis. Overall, 403 patients were included. The highest motivation values were obtained for the items "avoid transition to invasive squamous cell carcinoma" (mean +/- standard deviation; 8.98 +/- 1.46), "AK are considered precancerous lesions" (8.72 +/- 1.34) and "treating physician recommends treatment" (8.10 +/- 2.37; p < 0.0001). The highest expectation values were observed for the items "effective lesion clearance" (8.36 +/- 1.99), "safety" (8.20 +/- 2.03) and "treatment-related costs are covered by health insurance" (8.00 +/- 2.41; p < 0.0001). Patients aged >= 77 years and those with >= 7 lesions were identified at high risk of not undergoing any treatment due to intrinsic and extrinsic motivation deficits. Heat mapping of correlation analysis revealed four clusters with distinct motivation and expectation profiles. This study provides a patient-based heuristic tool for a personalized treatment decision in patients with AK.
Authors with CRIS profile
Carola Berking
Lehrstuhl für Haut- und Geschlechtskrankheiten
Markus Heppt
Department of Dermatology
Involved external institutions
Universitätsklinikum Tübingen
Germany (DE)
Klinikum Dortmund
Germany (DE)
Universitätsklinikum Heidelberg
Germany (DE)
Universitätsklinikum Schleswig-Holstein (UKSH)
Germany (DE)
Ludwig-Maximilians-Universität (LMU)
Germany (DE)
Universitätsklinikum Regensburg
Germany (DE)
Universitätsklinikum Bonn
Germany (DE)
Ruprecht-Karls-Universität Heidelberg
Germany (DE)
Universitätsmedizin Rostock
Germany (DE)
Ruhr-Universität Bochum (RUB)
Germany (DE)
Technische Universität München (TUM)
Germany (DE)
Germany (DE)
Klinikum Dortmund
Germany (DE)
Universitätsklinikum Heidelberg
Germany (DE)
Universitätsklinikum Schleswig-Holstein (UKSH)
Germany (DE)
Ludwig-Maximilians-Universität (LMU)
Germany (DE)
Universitätsklinikum Regensburg
Germany (DE)
Universitätsklinikum Bonn
Germany (DE)
Ruprecht-Karls-Universität Heidelberg
Germany (DE)
Universitätsmedizin Rostock
Germany (DE)
Ruhr-Universität Bochum (RUB)
Germany (DE)
Technische Universität München (TUM)
Germany (DE)
How to cite
APA:
Steeb, T., Wessely, A., Von Bubnoff, D., Dirschka, T., Drexler, K., Falkenberg, C.,... Heppt, M. (2020). Treatment Motivations and Expectations in Patients with Actinic Keratosis: A German-Wide Multicenter, Cross-Sectional Trial. Journal of Clinical Medicine, 9(5). https://doi.org/10.3390/jcm9051438
MLA:
Steeb, Theresa, et al. "Treatment Motivations and Expectations in Patients with Actinic Keratosis: A German-Wide Multicenter, Cross-Sectional Trial." Journal of Clinical Medicine 9.5 (2020).
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