In-vitro bioactivity and cytotoxicity of polarized (Bi0.5Na0.5)TiO3 ceramics as a novel biomaterial for bone repair

Hermann-Muñoz JA, Rincón-López JA, Fernández-Benavides DA, Detsch R, Alvarado-Orozco JM, Boccaccini AR, Muñoz-Saldaña J (2020)


Publication Type: Journal article

Publication year: 2020

Journal

Book Volume: 275

Article Number: 128078

DOI: 10.1016/j.matlet.2020.128078

Abstract

Poled (Bi0.5Na0.5)TiO3 ceramics were firstly evaluated in the present study for their potential application as a novel biomaterial for bone repair. The formation of bone-like apatite was only observed on polarized surfaces showing a clear influence of polarity on its growth and maturation process after bioactivity tests. A non-cytotoxic effect of (Bi0.5Na0.5)TiO3 ceramics on MC3T3-E1 cells was shown in the viability test. Cells spread along the surface showed slight differences in shape and size due to polarity. Bioactive and non-cytotoxic behavior exhibited by poled (Bi0.5Na0.5)TiO3 ceramics makes them a promising material with tunable in-vitro properties for biomedical applications.

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APA:

Hermann-Muñoz, J.A., Rincón-López, J.A., Fernández-Benavides, D.A., Detsch, R., Alvarado-Orozco, J.M., Boccaccini, A.R., & Muñoz-Saldaña, J. (2020). In-vitro bioactivity and cytotoxicity of polarized (Bi0.5Na0.5)TiO3 ceramics as a novel biomaterial for bone repair. Materials Letters, 275. https://doi.org/10.1016/j.matlet.2020.128078

MLA:

Hermann-Muñoz, J. A., et al. "In-vitro bioactivity and cytotoxicity of polarized (Bi0.5Na0.5)TiO3 ceramics as a novel biomaterial for bone repair." Materials Letters 275 (2020).

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