TRPA1-dependent calcium transients and CGRP release in DRG neurons require extracellular calcium

Gebhardt L, Kichko T, Fischer MJ, Reeh P (2020)

Publication Type: Journal article

Publication year: 2020

Journal

The Journal of Cell Biology Rockefeller University Press

Book Volume: 219

Journal Issue: 6

DOI: 10.1083/jcb.201702151

Abstract

Shang et al. (2016. J. Cell Biol.https://doi.org/10.1083/jcb.201603081) reported that activation of lysosomal TRPA1 channels led to intracellular calcium transients and CGRP release from DRG neurons. We argue that both findings are more likely due to influx of insufficiently buffered extracellular calcium rather than lysosomal release.

Authors with CRIS profile

Lisa Gebhardt Interdisziplinäres Zentrum für Klinische Forschung IZKF-Förderlinien Tetyana Kichko Lehrstuhl für Physiologie Peter Reeh Professur für Physiologie

Involved external institutions

Medizinische Universität Wien AT Austria (AT)

How to cite

APA:

Gebhardt, L., Kichko, T., Fischer, M.J., & Reeh, P. (2020). TRPA1-dependent calcium transients and CGRP release in DRG neurons require extracellular calcium. The Journal of Cell Biology, 219(6). https://doi.org/10.1083/jcb.201702151

MLA:

Gebhardt, Lisa, et al. "TRPA1-dependent calcium transients and CGRP release in DRG neurons require extracellular calcium." The Journal of Cell Biology 219.6 (2020).

BibTeX: Download