Impact of intermittent energy restriction on anthropometric outcomes and intermediate disease markers in patients with overweight and obesity: systematic review and meta-analyses

Schwingshackl L, Zähringer J, Nitschke K, Torbahn G, Lohner S, Kühn T, Fontana L, Veronese N, Schmucker C, Meerpohl JJ (2020)

Publication Type: Journal article, Review article

Publication year: 2020

Journal

Critical Reviews in Food Science and Nutrition Taylor & Francis: STM, Behavioural Science and Public Health Titles / Taylor & Francis

DOI: 10.1080/10408398.2020.1757616

Abstract

This systematic review aims to investigate the effects of intermittent energy restriction (IER) on anthropometric outcomes and intermediate disease markers. A systematic literature search was conducted in three electronic databases. Randomized controlled trials (RCTs) were included if the intervention lasted ≥12 weeks and IER was compared with either continuous energy restriction (CER) or a usual diet. Random-effects meta-analysis was performed for eight outcomes. Certainty of evidence was assessed using GRADE. Seventeen RCTs with 1328 participants were included. IER in comparison to a usual diet may reduce body weight (mean difference [MD]: −4.83 kg, 95%-CI: −5.46, −4.21; n = 6 RCTs), waist circumference (MD: −1.73 cm, 95%-CI: −3.69, 0.24; n = 2), fat mass (MD: −2.54 kg, 95%-CI: −3.78, −1.31; n = 6), triacylglycerols (MD: −0.20 mmol/L, 95%-CI: −0.38, −0.03; n = 5) and systolic blood pressure (MD: −6.11 mmHg, 95%-CI: −9.59, −2.64; n = 5). No effects were observed for LDL-cholesterol, fasting glucose, and glycosylated-hemoglobin. Both, IER and CER have similar effect on body weight (MD: −0.55 kg, 95%-CI: −1.01, −0.09; n = 13), and fat mass (MD: −0.66 kg, 95%-CI: −1.14, −0.19; n = 10), and all other outcomes. In conclusion, IER improves anthropometric outcomes and intermediate disease markers when compared to a usual diet. The effects of IER on weight loss are similar to weight loss achieved by CER.

Authors with CRIS profile

Gabriel Torbahn Lehrstuhl für Innere Medizin (Geriatrie)

Involved external institutions

Albert-Ludwigs-Universität Freiburg DE Germany (DE) University of Pécs / Pécsi Tudományegyetem HU Hungary (HU) Azienda Ulss 3 Serenissima IT Italy (IT) Deutsches Krebsforschungszentrum (DKFZ) DE Germany (DE) University of Sydney (USYD) AU Australia (AU)

How to cite

APA:

Schwingshackl, L., Zähringer, J., Nitschke, K., Torbahn, G., Lohner, S., Kühn, T.,... Meerpohl, J.J. (2020). Impact of intermittent energy restriction on anthropometric outcomes and intermediate disease markers in patients with overweight and obesity: systematic review and meta-analyses. Critical Reviews in Food Science and Nutrition. https://doi.org/10.1080/10408398.2020.1757616

MLA:

Schwingshackl, Lukas, et al. "Impact of intermittent energy restriction on anthropometric outcomes and intermediate disease markers in patients with overweight and obesity: systematic review and meta-analyses." Critical Reviews in Food Science and Nutrition (2020).

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