Chronic viral infections in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
Rasa S, Nora-Krukle Z, Henning N, Eliassen E, Shikova E, Harrer T, Scheibenbogen C, Murovska M, Prusty BK (2018)
Publication Type: Journal article
Publication year: 2018
Journal
Book Volume: 16
DOI: 10.1186/s12967-018-1644-y
Abstract
Background and main text: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex and controversial clinical condition without having established causative factors. Increasing numbers of cases during past decade have created awareness among patients as well as healthcare professionals. Chronic viral infection as a cause of ME/CFS has long been debated. However, lack of large studies involving well-designed patient groups and validated experimental set ups have hindered our knowledge about this disease. Moreover, recent developments regarding molecular mechanism of pathogenesis of various infectious agents cast doubts over validity of several of the past studies. Conclusions: This review aims to compile all the studies done so far to investigate various viral agents that could be associated with ME/CFS. Furthermore, we suggest strategies to better design future studies on the role of viral infections in ME/CFS.
Authors with CRIS profile
Involved external institutions
Medical University Sofia / Медицински университет
Bulgaria (BG)
Julius-Maximilians-Universität Würzburg
Germany (DE)
Rīga Stradiņš University
Latvia (LV)
Charité - Universitätsmedizin Berlin
Germany (DE)
Bulgaria (BG)
Julius-Maximilians-Universität Würzburg
Germany (DE)
Rīga Stradiņš University
Latvia (LV)
Charité - Universitätsmedizin Berlin
Germany (DE)
How to cite
APA:
Rasa, S., Nora-Krukle, Z., Henning, N., Eliassen, E., Shikova, E., Harrer, T.,... Prusty, B.K. (2018). Chronic viral infections in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Journal of Translational Medicine, 16. https://doi.org/10.1186/s12967-018-1644-y
MLA:
Rasa, Santa, et al. "Chronic viral infections in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)." Journal of Translational Medicine 16 (2018).
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