Induction of labour with sequential double-balloon catheter and oral misoprostol versus oral misoprostol alone in obese women

Kehl S, Born T, Weiss C, Faschingbauer F, Pretscher J, Beckmann M, Sütterlin M, Dammer U (2019)

Publication Type: Journal article

Publication year: 2019

Journal

European Journal of Obstetrics & Gynecology and Reproductive Biology: X Elsevier

Book Volume: 3

DOI: 10.1016/j.eurox.2019.100034

Abstract

Objective: To evaluate the efficacy of induction of labour in obese women using sequential double-balloon catheter and oral misoprostol in comparison with oral misoprostol alone. Study design: In this cohort study, 400 pregnant women with BMI higher than 35 kg/m2 undergoing labour induction at term were included. Induction of labour with a double-balloon catheter and, if necessary, sequential oral misoprostol (n = 216) was compared to oral misoprostol alone (n = 184). The primary outcome measure was the caesarean section rate. Secondary outcome parameters were, among others, the induction-to-delivery-interval, the rate of vaginal delivery within 24 and 48 h as well as fetal outcome parameters. Results: The caesarean section rate was significantly lower in the group with sequential use of double-balloon catheter and oral misoprostol (27.6% versus 37.5%, p = 0.0345). After stratification for parity this reduction was seen especially in nulliparous (38.6% versus 56.9%, p = 0.0039). The rate of abnormal CTG was significantly lower as well (19.9% versus 30.4%, p = 0.0150), particularly in nulliparous (25.9% versus 40.4%, p = 0.0138). Uni- and multivariable analyzes showed that the caesarean section rate was significantly influenced by the method of induction of labour (p = 0.0026), parity (p < 0.0001) and Bishop score (p = 0.0425). Conclusion: In obese women, induction of labour with sequential use of double-balloon catheter and oral misoprostol is associated with significantly more normal vaginal deliveries and less caesarean sections.

Authors with CRIS profile

Sven Kehl Department of Obstetrics and Gynaecology Tilman Born Department of Obstetrics and Gynaecology Matthias Beckmann Lehrstuhl für Geburtshilfe und Frauenheilkunde

Involved external institutions

Universitätsklinikum Heidelberg DE Germany (DE)

How to cite

APA:

Kehl, S., Born, T., Weiss, C., Faschingbauer, F., Pretscher, J., Beckmann, M.,... Dammer, U. (2019). Induction of labour with sequential double-balloon catheter and oral misoprostol versus oral misoprostol alone in obese women. European Journal of Obstetrics & Gynecology and Reproductive Biology: X, 3. https://doi.org/10.1016/j.eurox.2019.100034

MLA:

Kehl, Sven, et al. "Induction of labour with sequential double-balloon catheter and oral misoprostol versus oral misoprostol alone in obese women." European Journal of Obstetrics & Gynecology and Reproductive Biology: X 3 (2019).

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