König J (1998)
Publication Type: Journal article
Publication year: 1998
Book Volume: 438
Pages Range: 315-320
Journal Issue: 3
DOI: 10.1016/S0014-5793(98)01326-X
The anion exchange protein AE1 is the most abundant membrane protein in human erythrocytes mediating the electroneutral chloride/bicarbonate exchange. We identified a promoter region in the 5' flanking region of the human AE1 gene which controls transcription in a cell type independent manner. In addition a second, distal promoter element mediates gene expression only in erythroid cells and in dependence upon differentiation. Within this distal promoter region we defined a 44 bp sequence containing a novel CT-rich motif with very strong promoter activity whereas a second 28 bp segment suppresses gene expression. Copyright (C) 1998 Federation of European Biochemical Societies.
APA:
König, J. (1998). Molecular analysis of regulation of gene expression of the human erythroid anion exchanger (AE) 1. Febs Letters, 438(3), 315-320. https://doi.org/10.1016/S0014-5793(98)01326-X
MLA:
König, Jörg. "Molecular analysis of regulation of gene expression of the human erythroid anion exchanger (AE) 1." Febs Letters 438.3 (1998): 315-320.
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