Update Breast Cancer 2018 (Part 1) - Primary Breast Cancer and Biomarkers

Taran FA, Schneeweiss A, Lux MP, Janni W, Hartkopf AD, Nabieva N, Overkamp F, Kolberg HC, Hadji P, Tesch H, Woeckel A, Ettl J, Lueftner D, Wallwiener M, Mueller V, Beckmann M, Belleville E, Wallwiener D, Brucker SY, Fasching P, Fehm TN, Schuetz F (2018)

Publication Type: Journal article

Publication year: 2018

Journal

Geburtshilfe und Frauenheilkunde Georg Thieme Verlag

Book Volume: 78

Pages Range: 237-245

Journal Issue: 3

DOI: 10.1055/s-0044-101613

Abstract

This summary provides an overview of how new therapies or new aspects of established therapies relate to the latest findings. Neoadjuvant therapy, local therapy, new aspects of systemic therapy, and prognostic and predictive factors are presented. In the neoadjuvant setting, the association between pathological complete response (pCR) and prognosis is still of interest as is the identification of new molecular predictors for new therapies such as CDK4/6 inhibitors. As regards surgical treatment, the target is still to reduce the aggressiveness of surgery. To achieve this, a better understanding particularly of ductal carcinoma in situ is required. With regard to systemic therapy, more data on the best combinations and therapy sequences for existing therapies is available. Finally, the use of prognostic and predictive factors may help to avoid overtreatment and ensure that patients only receive therapies which have been shown to be effective for their specific condition and have fewer side effects.

Authors with CRIS profile

Naiba Nabieva Department of Obstetrics and Gynaecology Matthias Beckmann Lehrstuhl für Geburtshilfe und Frauenheilkunde Peter Fasching Professur für Translationale Frauenheilkunde und Geburtshilfe

Involved external institutions

Eberhard Karls Universität Tübingen DE Germany (DE) Universitätsklinikum Heidelberg DE Germany (DE) Universitätsklinikum Ulm DE Germany (DE) OncoConsult DE Germany (DE) Marienhospital Bottrop DE Germany (DE) Krankenhaus Nordwest DE Germany (DE) Centrum für Hämatologie und Onkologie Bethanien DE Germany (DE) Universitätsklinikum Würzburg DE Germany (DE) Technische Universität München (TUM) DE Germany (DE) Charité - Universitätsmedizin Berlin DE Germany (DE) Ruprecht-Karls-Universität Heidelberg DE Germany (DE) Universitätsklinikum Hamburg-Eppendorf (UKE) DE Germany (DE) ClinSol GmbH & Co.KG DE Germany (DE) Universitätsklinikum Düsseldorf DE Germany (DE)

How to cite

APA:

Taran, F.-A., Schneeweiss, A., Lux, M.P., Janni, W., Hartkopf, A.D., Nabieva, N.,... Schuetz, F. (2018). Update Breast Cancer 2018 (Part 1) - Primary Breast Cancer and Biomarkers. Geburtshilfe und Frauenheilkunde, 78(3), 237-245. https://doi.org/10.1055/s-0044-101613

MLA:

Taran, Florin-Andrei, et al. "Update Breast Cancer 2018 (Part 1) - Primary Breast Cancer and Biomarkers." Geburtshilfe und Frauenheilkunde 78.3 (2018): 237-245.

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