Evaluation of neck dissection with frozen section biopsy – Management of levels IV and V

Frohwitter G, Röckl J, Rau A, Wolff KD, Kesting MR, Koerdt S (2019)

Publication Type: Journal article

Publication year: 2019

Journal

Journal of Cranio-Maxillofacial Surgery Elsevier

Book Volume: 47

Pages Range: 1963-1967

Journal Issue: 12

DOI: 10.1016/j.jcms.2019.11.019

Abstract

Introduction: Neck dissection is an essential component of oral cancer therapy. Based on a standardised approach to cervical lymph node management, we seek to define the relevance of neck dissection extension in cN + cases. Material and methods: A retrospective analysis from January 2009 to February 2017 identified 84 patients with oral squamous cell carcinoma with a cN + neck or histologically proven lymph node involvement in intraoperative frozen sectioning and who received modified radical neck dissection according to the presented neck dissection algorithm. Results: Overall 11 patients showed lymph node metastasis level IV or V, whereas 19 developed disease recurrence, of which 5 cases were neck recurrences. A total of 30 patients died within the time of observance (overall survival of n = 54). None of those patients with pN + status in levels IV and V reached a 5-year survival. Discussion: With a look to the possibility of a 5-year survival in patients with a N+ status in level IV and V, the justification for a radical approach to the neck appears questionable. However, modified radical neck dissection appears to be a suitable for a high-risk oral cancer subgroup. A randomised controlled trial is needed to define guidelines for the neck dissection extent in c/pN + cases.

Authors with CRIS profile

Andrea Rau Department of Oral and Cranio-Maxillofacial Surgery Marco Rainer Kesting Lehrstuhl für Zahnmedizin, insbesondere Mund-, Kiefer-, und Gesichtschirurgie

Involved external institutions

Technische Universität München (TUM) DE Germany (DE) Charité - Universitätsmedizin Berlin DE Germany (DE)

How to cite

APA:

Frohwitter, G., Röckl, J., Rau, A., Wolff, K.D., Kesting, M.R., & Koerdt, S. (2019). Evaluation of neck dissection with frozen section biopsy – Management of levels IV and V. Journal of Cranio-Maxillofacial Surgery, 47(12), 1963-1967. https://doi.org/10.1016/j.jcms.2019.11.019

MLA:

Frohwitter, Gesche, et al. "Evaluation of neck dissection with frozen section biopsy – Management of levels IV and V." Journal of Cranio-Maxillofacial Surgery 47.12 (2019): 1963-1967.

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