Now a Nobel gas: oxygen

Fandrey J, Schödel J, Eckardt KU, Katschinski DM, Wenger RH (2019)

Publication Type: Journal article, Review article

Publication year: 2019

Journal

Pflügers Archiv: European Journal of Physiology Springer

DOI: 10.1007/s00424-019-02334-8

Abstract

The recent bestowal of the Nobel Prize 2019 in Physiology or Medicine to Gregg L. Semenza, Sir Peter J. Ratcliffe, and William G. Kaelin Jr. celebrates a series of remarkable discoveries that span from the physiological research question on how oxygen deficiency (hypoxia) induces the red blood cell forming hormone erythropoietin (Epo) to the first clinical application of a novel family of Epo-inducing drugs to treat patients suffering from renal anemia. This review looks back at the most important findings made by the three Nobel laureates, highlights current research trends, and sheds an eye on future perspectives of hypoxia research, including emerging and potential clinical applications.

Authors with CRIS profile

Johannes Schödel Department of Medicine 4 – Nephrology and Hypertension Kai-Uwe Eckardt Department of Medicine 4 – Nephrology and Hypertension

Involved external institutions

Universitätsklinikum Göttingen DE Germany (DE) Universität Duisburg-Essen (UDE) DE Germany (DE) Universitätsspital Zürich (USZ) CH Switzerland (CH)

How to cite

APA:

Fandrey, J., Schödel, J., Eckardt, K.-U., Katschinski, D.M., & Wenger, R.H. (2019). Now a Nobel gas: oxygen. Pflügers Archiv: European Journal of Physiology. https://doi.org/10.1007/s00424-019-02334-8

MLA:

Fandrey, Joachim, et al. "Now a Nobel gas: oxygen." Pflügers Archiv: European Journal of Physiology (2019).

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