Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: a European Scleroderma Trials and Research (EUSTAR) analysis

Becker M, Graf N, Sauter R, Allanore Y, Curram J, Denton CP, Khanna D, Matucci-Cerinic M, Pena JDO, Pope JE, Distler O, Matucci-Cerinic M, Guiducci S, Walker U, Jaeger V, Bannert B, Lapadula G, Becvarare R, Cutolo M, Valentini G, Siegert E, Rednic S, Allanore Y, Montecucco C, Carreira PE, Novak S, Czirjak L, Varju C, Chizzolini C, Allai D, Kucharz EJ, Cozzi F, Rozman B, Mallia C, Gabrielli A, Bancel DF, Airo P, Hesselstrand R, Martinovic D, Balbir-Gurman A, Braun-Moscovici Y, Hunzelmann N, Pellerito R, Caramaschi P, Black C, Damjanov N, Henes J, Ortiz Santamaria V, Heitmann S, Seidel M, Pereira Da Silva JA, Stamenkovic B, Selmi CF, Tikly M, Denisov LN, Mueller-Ladner U, Engelhart M, Hachulla E, Riccieri V, Ionescu RM, Mihai C, Sunderkoetter C, Kuhn A, Schett G, Distler J, Meroni P, Ingegnoli F, Mouthon L, De Keyser F, Smith V, Cantatore FP, Corrado A, Ullman S, Iversen L, Pozzi MR, Eyerich K, Hein R, Knott E, Wiland P, Szmyrka-Kaczmarek M, Sokolik R, Morgiel E, Madej M, Jose Alegre-Sancho J, Krummel-Lorenz B, Saar P, Aringer M, Günther C, Anne E, Westhovens R, De Langhe E, Lenaerts J, Anic B, Baresic M, Mayer M, Uprus M, Otsa K, Yavuz S, Radominski SC, Mueller CDS, Azevedo VF, Popa S, Zenone T, Stebbings S, Highton J, Mathieu A, Vacca A, Stamp L, Chapman P, O'Donnell J, Solanki K, Doube A, Veale D, O'Rourke M, Loyo E, Li M, Rosato E, Amoroso A, Gigante A, Oksel F, Yargucu F, Tanaseanu CM, Popescu M, Dumitrascu A, Tiglea I, Foti R, Visalli E, Benenati A, Amato G, Ancuta C, Chirieac R, Villiger P, Adler S, Dan D, De La Pena Lefebvre PG, Rodriguez Rubio S, Valero Exposito M, Sibilia J, Chatelus E, Gottenberg JE, Chifflot H, Litinsky I, Del Galdo F, Venalis A, Saketkoo LA, Lasky JA, Kerzberg E, Montoya F, Cosentino V, Limonta M, Brucato AL, Lupi E, Spertini F, Ribi C, Buss G, Martin T, Guffroy A, Poindron V, Chung L, Schmeiser T, Zebryk P, Riso N, Riemekasten G, Rezus E, Puttini PS (2019)

Publication Type: Journal article

Publication year: 2019

Journal

Book Volume: 78

Pages Range: 1242-1248

Journal Issue: 9

DOI: 10.1136/annrheumdis-2019-215145

Abstract

Objectives Mortality and worsening of organ function are desirable endpoints for clinical trials in systemic sclerosis (SSc). The aim of this study was to identify factors that allow enrichment of patients with these endpoints, in a population of patients from the European Scleroderma Trials and Research group database.

Authors with CRIS profile

Involved external institutions

Universitätsspital Basel Switzerland (CH) University of Pécs / Pécsi Tudományegyetem Hungary (HU) Geneva University Hospitals / Hôpitaux universitaires de Genève (HUG) Switzerland (CH) Bayer Plc United Kingdom (GB) Hospital Universitario 12 de Octubre Spain (ES) University of Paris 5 - René Descartes / Université Paris V René Descartes France (FR) graf biostatistics Switzerland (CH) Charité - Universitätsmedizin Berlin Germany (DE) Univerzita Karlova v Praze / Charles University in Prague Czech Republic (CZ) KBC Rijeka Croatia (HR) University College London (UCL) United Kingdom (GB) University of Padua / Universita degli Studi di Padova Italy (IT) Università degli Studi di Firenze / University of Florence Italy (IT) Universitätsspital Zürich (USZ) Switzerland (CH) Western University Canada (CA) University of Genova / Università degli Studi di Genova Italy (IT) Policlinico San Matteo Pavia Fondazione IRCCS Italy (IT) University of Michigan United States (USA) (US) Università Politecnica delle Marche (UNIVPM) / Marche Polytechnic University Italy (IT) Iuliu Hațieganu University of Medicine and Pharmacy / Universitatea de Medicină și Farmacie "Iuliu Hațieganu" (UMF Cluj) Romania (RO) Bayer Corporation United States (USA) (US) Ljubljana University Medical Centre (Ljubljana UMC) / Univerzitetni klinični center Ljubljana Slovenia (SI) Medical University of Silesia in Katowice / Śląski Uniwersytet Medyczny w Katowicach (SUM) Poland (PL) Hôpital Cochin France (FR) University of Bari Aldo Moro / Università degli Studi di Bari Aldo Moro Italy (IT) University of Oxford United Kingdom (GB) Rambam Health Care Campus Israel (IL) Hôpital Claude Huriez France (FR) Wrocław Medical University / Uniwersytet Medyczny we Wrocławiu Poland (PL) Gentofte Hospital Denmark (DK) Kerckhoff-Klinik Germany (DE) Universitätsklinikum Tübingen Germany (DE) Chris Hani Baragwanath Hospital South Africa (ZA) endokrinologikum Frankfurt am Main Germany (DE) Università degli studi di Milano Italy (IT) Universitätsklinikum Carl Gustav Carus Dresden Germany (DE) East Tallinn Central Hospital Estonia (EE) Copenhagen University Hospital Denmark (DK) Universidade Federal do Paraná (UFPR) Brazil (BR) Skåne University Hospital / Skånes universitetssjukhus Sweden (SE) Technische Universität München (TUM) Germany (DE) University of Zagreb / Sveučilište u Zagrebu Croatia (HR) L'Ospedale Mauriziano di Torino Italy (IT) Universitätsklinikum Köln Germany (DE) Hospital General de Granollers Spain (ES) Università degli studi "La Sapienza" Italy (IT) University Hospital Leuven (UZ) / Universitaire ziekenhuizen Leuven Belgium (BE) University of Foggia / Università degli studi di Foggia Italy (IT) University Hospital Split Croatia (HR) Westfälische Wilhelms-Universität (WWU) Münster Germany (DE) Hospital Clínico Universitario de Valencia Spain (ES) Universiteit Gent (UGent) / Ghent University Belgium (BE) Hôpital civil France (FR) Ospedale Liriuniti Italy (IT) Tulane University United States (USA) (US) V.A. Nasonova Research Institute of Rheumatology Russian Federation (RU) Universidad de Buenos Aires (UBA) / University of Buenos Aires Argentina (AR) Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia Italy (IT) Spitalul Clinic de Urgenta "Sf. Pantelimon" Romania (RO) Tel Aviv Sourasky Medical Center / Ichilov Hospital Israel (IL) University of Otago New Zealand (NZ) Luigi Sacco Hospital Italy (IT) Hospital Curry Cabral Portugal (PT) Hospital Universitario HM Sanchinarro Spain (ES) Università degli Studi di Cagliari Italy (IT) Ege University / Ege Üniversitesi Turkey (TR) Universitatea „Alexandru Ioan Cuza” din Iași Romania (RO) Timofei Moșneaga Republican Clinical Hospital Moldova, Republic of (MD) Universität Bern Switzerland (CH) Grigore T. Popa University of Medicine and Pharmacy / Universitatea de Medicină și Farmacie "Grigore T. Popa" (UMF Iași) Romania (RO) Stanford University United States (USA) (US) Universitätsklinikum Schleswig-Holstein (UKSH) Germany (DE) Hospital Jose Maria Cabral Y Baez Dominican Republic (DO) St Vincent's University Hospital Ireland (IE) Hôpitaux universitaires de Strasbourg (HUS) / University Hospital Strasbourg France (FR) University of Waikato New Zealand (NZ) Poznan University of Medical Sciences / Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu Poland (PL) Krankenhaus St. Josef Germany (DE) Azienda Ospedaliero Universitaria "Policlinico - Vittorio Emanuele" Italy (IT) Assistance Publique-Hôpitaux de Paris (AP-HP) France (FR) Azienda Ospedaliera San Gerardo (ASST Monza) Italy (IT) University of Leeds United Kingdom (GB) Spitalul Clinic Dr. I. Cantacuzino Romania (RO) Peking Union Medical College / 北京协和医学院 China (CN) Universitätsklinikum Bonn Germany (DE) University of Verona / Università degli Studi di Verona Italy (IT) Carol Davila University of Medicine and Pharmacy / Universitatea de Medicină și Farmacie „Carol Davila” (UMF București) Romania (RO) Marmara University Turkey (TR) Marienhospital Stuttgart Germany (DE) Universidade de Coimbra Portugal (PT)

How to cite

APA:

Becker, M., Graf, N., Sauter, R., Allanore, Y., Curram, J., Denton, C.P.,... Puttini, P.S. (2019). Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: a European Scleroderma Trials and Research (EUSTAR) analysis. Annals of the Rheumatic Diseases, 78(9), 1242-1248. https://doi.org/10.1136/annrheumdis-2019-215145

MLA:

Becker, Mike, et al. "Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: a European Scleroderma Trials and Research (EUSTAR) analysis." Annals of the Rheumatic Diseases 78.9 (2019): 1242-1248.

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