Rödle W, Wimmer S, Zahn J, Prokosch HU, Hinkes B, Neubert A, Rascher W, Kraus S, Toddenroth D, Sedlmayr B (2019)
Publication Type: Journal article
Publication year: 2019
Book Volume: 10
Pages Range: 570-579
Journal Issue: 4
Background Drug therapy in pediatric patients is a complex process. Children are subject to continuous growth and variation in drug-metabolizing enzyme activity, requiring continuous adaption of dosages. In Germany, currently no publicly available database exists that provides evidence-based information on drug dosages in pediatrics. For local drug dosing support, a prototype database has been developed within the Children's Hospital, Erlangen. A user-centered development process was initiated to establish an online platform for evidence-based dosing recommendations, as well as pharmacological and pharmaceutical drug information in pediatrics. Objectives The objectives of the study were to survey the demand for such a platform and to assess the usability of the different versions of the developed system. Methods The developed prototype was evaluated in a pluralistic walkthrough with prospective end users. After a redesign, the second prototype of the online platform underwent an online usability testing based on a tailored questionnaire and the System Usability Scale (SUS) (n = 12). Results Eleven of 12 participants expressed a demand for an online platform for pediatric dosing recommendations. The majority of the participants requested the integration of extended features, such as drug-drug interaction alerts, or information on adverse effects, pharmacokinetics, and pharmacodynamics. Particularly noteworthy is the demand for an online calculator; 5 of a total of 15 participants explicitly requested a calculator for dosages (based on age, weight, body surface) and glomerular filtration rate. The usability of the second prototype was rated good to excellent with a median SUS of 81.25. Conclusion Local domain experts demand an online platform for pediatric dosing recommendations. The application of the user-centered design approach enabled the development of a prototype suitable for practical use. Multiple additional required functionalities have been identified, whereby the importance of an online calculator for patient-individual dosing recommendations was particularly emphasized.
APA:
Rödle, W., Wimmer, S., Zahn, J., Prokosch, H.-U., Hinkes, B., Neubert, A.,... Sedlmayr, B. (2019). User-Centered Development of an Online Platform for Drug Dosing Recommendations in Pediatrics. Applied Clinical Informatics, 10(4), 570-579. https://doi.org/10.1055/s-0039-1693714
MLA:
Rödle, Wolfgang, et al. "User-Centered Development of an Online Platform for Drug Dosing Recommendations in Pediatrics." Applied Clinical Informatics 10.4 (2019): 570-579.
BibTeX: Download