Interface morphology and gas production by a refractive 347 nm ultraviolet femtosecond laser: Comparison with established laser systems
Hammer C, Kunert KS, Zhang Y, Loerner J, Wuelner C, Rothuber EL, Paulsen F, Seiler T (2018)
Publication Type: Journal article
Publication year: 2018
Journal
Book Volume: 44
Pages Range: 1371-1377
Journal Issue: 11
DOI: 10.1016/j.jcrs.2018.05.030
Abstract
PURPOSE: To evaluate gas production and interface quality after refractive lenticule creation. A new ultraviolet (UV) 347 nm femtosecond laser was compared with the FS200 and the Visumax lasers. SETTING: Department of Anatomy II, University of Erlangen-Nürnberg, Erlangen, Germany. DESIGN: Experimental study. METHODS: Refractive lenticules were created in 52 porcine corneas with the UV laser (n = 20), the Visumax laser (n = 20), and a modified FS200 laser (n = 12). Twelve corneas in each laser group were fixed immediately after lenticule creation to entrap the gas produced. Lenticule extraction was omitted. From 16 other corneas (UV and Visumax lasers; n = 8 each) -5.0 diopter (D) and -10.0 D lenticules were extracted. On lenticule extraction, a flap was created and lifted. In 12 additional corneas, a flap was cut using the FS200 laser and lifted afterward; laser in situ keratomileusis was performed on 8 of these samples. The corneas were processed for light microscopy (gas bubble 2-dimensional morphometry) and scanning electron microscopy (interface quality). RESULTS: The Visumax generated approximately one half as much gas as the FS200. The UV laser undercut the Visumax by another 50%. The interfaces created by the FS200 appeared smooth and without irregularities. The optical zone margin was always conspicuous in the Visumax samples but hardly discernible in the UV specimens. Slight irregularities and very small lenticule pieces were found occasionally in both groups. The UV interfaces appeared slightly rougher than the Visumax interfaces. CONCLUSIONS: Ultraviolet laser lenticule extraction seems promising. The interface quality was similar to that of the clinical Visumax system while gas production was reduced significantly.
Authors with CRIS profile
Christian Hammer
Lehrstuhl für Funktionelle und Klinische Anatomie
Friedrich Paulsen
Lehrstuhl für Funktionelle und Klinische Anatomie
Involved external institutions
WaveLight GmbH
Germany (DE)
IROC AG - Institut für Refraktive und Ophthalmo-Chirurgie
Switzerland (CH)
HELIOS Kliniken
Germany (DE)
Germany (DE)
IROC AG - Institut für Refraktive und Ophthalmo-Chirurgie
Switzerland (CH)
HELIOS Kliniken
Germany (DE)
How to cite
APA:
Hammer, C., Kunert, K.S., Zhang, Y., Loerner, J., Wuelner, C., Rothuber, E.L.,... Seiler, T. (2018). Interface morphology and gas production by a refractive 347 nm ultraviolet femtosecond laser: Comparison with established laser systems. Journal of Cataract and Refractive Surgery, 44(11), 1371-1377. https://doi.org/10.1016/j.jcrs.2018.05.030
MLA:
Hammer, Christian, et al. "Interface morphology and gas production by a refractive 347 nm ultraviolet femtosecond laser: Comparison with established laser systems." Journal of Cataract and Refractive Surgery 44.11 (2018): 1371-1377.
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