Renal denervation improves 24-hour central and peripheral blood pressures, arterial stiffness, and peripheral resistance
Ott C, Franzen KF, Graf T, Weil J, Schmieder R, Reppel M, Mortensen K (2018)
Publication Type: Journal article
Publication year: 2018
Journal
Book Volume: 20
Pages Range: 366-372
Journal Issue: 2
DOI: 10.1111/jch.13193
Abstract
Ambulatory blood pressure (BP) and central BP are better predictors for overall cardiovascular risk and mortality than brachial BP. Renal denervation (RDN) has been shown to reduce office brachial and central BP as well as brachial ambulatory BP, but data on central ambulatory BP are limited. Patients (N = 94) with treatment resistant hypertension (TRH) who underwent RDN were included. Ambulatory BP, including central pressures, hemodynamics, and arterial stiffness were measured at baseline and 3, 6, 12 months after RDN by an oscillometric device (MobiloGraph™). At 3, 6, and 12-month follow-ups, brachial ambulatory BP was reduced (P for all < .001). Consistently, central ambulatory BP was reduced (P for all < .001). Ambulatory assessed averaged daytime pulse wave velocity improved after RDN (P < .05). Total vascular resistance decreased (P for all < .01). In patients with TRH, RDN improves brachial and central ambulatory BP, arterial stiffness, and total vascular resistance, indicating an improvement of cardiovascular outcome.
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Germany (DE)How to cite
APA:
Ott, C., Franzen, K.F., Graf, T., Weil, J., Schmieder, R., Reppel, M., & Mortensen, K. (2018). Renal denervation improves 24-hour central and peripheral blood pressures, arterial stiffness, and peripheral resistance. Journal of Clinical Hypertension, 20(2), 366-372. https://doi.org/10.1111/jch.13193
MLA:
Ott, Christian, et al. "Renal denervation improves 24-hour central and peripheral blood pressures, arterial stiffness, and peripheral resistance." Journal of Clinical Hypertension 20.2 (2018): 366-372.
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