Resolution of chronic inflammatory disease: universal and tissue-specific concepts

Schett G, Neurath M (2018)

Publication Type: Journal article

Publication year: 2018

Journal

Nature Communications Nature Publishing Group: Nature Communications

Book Volume: 9

Journal Issue: 1

DOI: 10.1038/s41467-018-05800-6

Abstract

Inflammation and its resolution is under-studied in medicine despite being essential for understanding the development of chronic inflammatory disease. In this review article, we discuss the resolution of inflammation in both a biological and translational context. We introduce the concept of impaired resolution leading to diseases like rheumatoid arthritis, Crohn's disease, and asthma, as well as the cellular and molecular components that contribute to resolution of joint, gut, and lung inflammation, respectively. Finally, we discuss potential intervention strategies for fostering the resolution process, and their implications for the therapy of inflammatory diseases.

Authors with CRIS profile

Georg Schett Lehrstuhl für Innere Medizin III Markus Neurath Lehrstuhl für Innere Medizin I

How to cite

APA:

Schett, G., & Neurath, M. (2018). Resolution of chronic inflammatory disease: universal and tissue-specific concepts. Nature Communications, 9(1). https://doi.org/10.1038/s41467-018-05800-6

MLA:

Schett, Georg, and Markus Neurath. "Resolution of chronic inflammatory disease: universal and tissue-specific concepts." Nature Communications 9.1 (2018).

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