Long-term effects of exercise in postmenopausal women: 16-year results of the Erlangen Fitness and Osteoporosis Prevention Study (EFOPS)
Kemmler W, Kohl M, von Stengel S (2017)
Publication Type: Journal article
Publication year: 2017
Journal
Book Volume: 24
Pages Range: 45-51
Journal Issue: 1
DOI: 10.1097/GME.0000000000000720
Abstract
OBJECTIVE: Multimorbidity related to menopause and/or increased age will put healthcare systems in western nations under ever-greater strain. Effective strategies to prevent diseases are thus of high priority and should be started earlier in life. The purpose of the study was to evaluate the long-term effect of exercise on different important health parameters in initially early postmenopausal women over a 16-year period. METHODS: In 1998, 137 early postmenopausal women with osteopenia living in Erlangen-Nürnberg were included in the study. Eighty-six women joined the exercise group (EG) and conducted two supervised group and two home training sessions per week, whereas the control group (CG: n = 51) maintained their physical activity level. Primary outcome parameters were clinical overall fractures incidence; secondary study endpoint was Framingham study-based 10-year risk of coronary death/myocardial infarction and low back pain. RESULTS: In 2014, 59 women of the EG and 46 women of the CG were included in the 16-year follow-up analysis. Framingham study-based 10-year risk of myocardial infarction/coronary death increased significantly (P < 0.001) in both groups; however, changes were significantly more favorable in the EG (5.00% ± 2.94% vs CG: 6.90% ± 3.98%; P = 0.02). The ratio for clinical "overall" fractures was 0.47 (95% CI: 0.24-0.92; P = 0.03), and thus significantly lower in the EG. Although we focused on a high-intensity exercise strategy, low back pain was favorably affected in the EG. CONCLUSIONS: Multipurpose exercise programs demonstrated beneficial effects on various relevant risk factors and diseases of menopause or/and increased age, and should thus be preferentially applied for primary or secondary prevention in postmenopausal women.
Authors with CRIS profile
Wolfgang Kemmler
Lehrstuhl für Medizinische Physik und Mikrogewebetechnik
Simon von Stengel
Lehrstuhl für Medizinische Physik und Mikrogewebetechnik
Involved external institutions
Germany (DE)How to cite
APA:
Kemmler, W., Kohl, M., & von Stengel, S. (2017). Long-term effects of exercise in postmenopausal women: 16-year results of the Erlangen Fitness and Osteoporosis Prevention Study (EFOPS). Menopause : the journal of the North American Menopause Society, 24(1), 45-51. https://doi.org/10.1097/GME.0000000000000720
MLA:
Kemmler, Wolfgang, Matthias Kohl, and Simon von Stengel. "Long-term effects of exercise in postmenopausal women: 16-year results of the Erlangen Fitness and Osteoporosis Prevention Study (EFOPS)." Menopause : the journal of the North American Menopause Society 24.1 (2017): 45-51.
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