Molecular pathways driving disease-specific alterations of intestinal epithelial cells

Lopez Posadas R, Neurath M, Atreya I (2017)

Publication Type: Journal article

Publication year: 2017

Journal

Cellular and Molecular Life Sciences Springer Verlag (Germany)

Book Volume: 74

Pages Range: 803-826

Journal Issue: 5

DOI: 10.1007/s00018-016-2363-2

Abstract

Due to the fact that chronic inflammation as well as tumorigenesis in the gut is crucially impacted by the fate of intestinal epithelial cells, our article provides a comprehensive overview of the composition, function, regulation and homeostasis of the gut epithelium. In particular, we focus on those aspects which were found to be altered in the context of inflammatory bowel diseases or colorectal cancer and also discuss potential molecular targets for a disease-specific therapeutic intervention.

Authors with CRIS profile

Rocío Lopez Posadas Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology Markus Neurath Lehrstuhl für Innere Medizin I

How to cite

APA:

Lopez Posadas, R., Neurath, M., & Atreya, I. (2017). Molecular pathways driving disease-specific alterations of intestinal epithelial cells. Cellular and Molecular Life Sciences, 74(5), 803-826. https://doi.org/10.1007/s00018-016-2363-2

MLA:

Lopez Posadas, Rocío, Markus Neurath, and Imke Atreya. "Molecular pathways driving disease-specific alterations of intestinal epithelial cells." Cellular and Molecular Life Sciences 74.5 (2017): 803-826.

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