Lee B, Moult EM, Ploner S, Alibhai AY, Rebhun CB, Moreira-Neto C, Husvogt L, Maier A, Wollstein G, Schuman J, Waheed NK, Duker JS, Fujimoto JG (2017)
Publication Language: English
Publication Type: Conference contribution, Abstract of lecture
Publication year: 2017
Book Volume: 58
Pages Range: tbd
Edition: 8
Conference Proceedings Title: Investigative Ophthalmology & Visual Science
Event location: Baltimore, MD, USA
URI: https://www5.informatik.uni-erlangen.de/Forschung/Publikationen/2017/Lee17-PVI.pdf
Purpose : The introduction of optical coherence tomography angiography (OCTA) allows clinicians to study the microvascular alterations that occur in diabetic retinopathy (DR). Standard OCTA systems yield a detailed picture of the presence of vasculature, but have limited dynamic range and provide little information about blood flow speeds. Our group has recently developed variable interscan time analysis (VISTA), which provides a framework for studying relative blood flow speeds using OCTA. This study investigates VISTA to assess microvascular blood flow speeds in eyes with DR.
Methods : Using a VISTA protocol we analyzed 3 eyes with mild non-proliferative DR (NPDR) (2 patients; 66.7±2.31 y/o), 5 eyes with moderate NPDR (3 patients; 57.6±16.58 y/o), 5 eyes with severe NPDR (4 patients; 51.8±13.44 y/o), and 8 eyes with proliferative DR (PDR) (6 patients; 57.0±13.38 y/o).
Results : We observed a range of flow distributions associated with capillary looping/microaneurysms, tortuous vessels, dilated vessels, and neovasculature vessels. Representative VISTA-OCTA images are shown in Figures 1 and 2.
Conclusions : VISTA is a useful framework for studying blood flow speeds in eyes with DR.
APA:
Lee, B., Moult, E.M., Ploner, S., Alibhai, A.Y., Rebhun, C.B., Moreira-Neto, C.,... Fujimoto, J.G. (2017, June). Parallel Variable Interscan Time Analysis (VISTA) OCTA and en Face Doppler OCT of Optic Disc and Peripapillary Vasculature. Paper presentation at ARVO Annual Meeting 2017, Baltimore, MD, USA, US.
MLA:
Lee, Byungkun, et al. "Parallel Variable Interscan Time Analysis (VISTA) OCTA and en Face Doppler OCT of Optic Disc and Peripapillary Vasculature." Presented at ARVO Annual Meeting 2017, Baltimore, MD, USA 2017.
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