Human-induced pluripotent stem cells pave the road for a better understanding of motor neuron disease

Winner B, Marchetto MC, Winkler J, Gage FH (2014)

Publication Type: Journal article

Publication year: 2014

Journal

Human Molecular Genetics Oxford University Press (OUP): Policy B - Oxford Open Option B

Publisher: Oxford University Press (OUP): Policy B - Oxford Open Option B

Book Volume: 23

Pages Range: R27-34

Journal Issue: R1

DOI: 10.1093/hmg/ddu205

Abstract

While motor neuron diseases are currently incurable, induced pluripotent stem cell research has uncovered some disease-relevant phenotypes. We will discuss strategies to model different aspects of motor neuron disease and the specific neurons involved in the disease. We will then describe recent progress to investigate common forms of motor neuron disease: amyotrophic lateral sclerosis, hereditary spastic paraplegia and spinal muscular atrophy.

Authors with CRIS profile

Beate Winner Professur für Stammzell-Modelle seltener neuraler Erkrankungen Jürgen Winkler Professur für Molekulare Neurologie

Involved external institutions

Salk Institute for Biological Studies US United States (USA) (US)

How to cite

APA:

Winner, B., Marchetto, M.C., Winkler, J., & Gage, F.H. (2014). Human-induced pluripotent stem cells pave the road for a better understanding of motor neuron disease. Human Molecular Genetics, 23(R1), R27-34. https://doi.org/10.1093/hmg/ddu205

MLA:

Winner, Beate, et al. "Human-induced pluripotent stem cells pave the road for a better understanding of motor neuron disease." Human Molecular Genetics 23.R1 (2014): R27-34.

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