Leppkes M, Ganslmayer M, Strauss R, Neurath M (2015)
Publication Type: Journal article, Editorial
Publication year: 2015
Book Volume: 110
Pages Range: 500-5
Journal Issue: 7
DOI: 10.1007/s00063-015-0076-1
Toxic megacolon constitutes a feared, life-threatening complication of severe intestinal inflammation and is a challenge for interdisciplinary medical care.Specific aspects of conservative treatment based on current scientific evidence derived from guidelines, qualified reviews, and scientific studies are presented, which provide a rational approach and maximize therapeutic success.This work is based on a selective literature review and the authors' experience of many years in gastroenterology and intensive care.Toxic megacolon requires a rapid interdisciplinary assessment. Depending on the underlying etiology, an individual treatment concept needs to be developed. If an infectious or inflammatory cause is probable, a conservative approach can reduce perioperative morbidity and mortality. A step-wise approach with controlled reevaluations of the response to therapy after 72 h and 7 days avoids uncontrolled delay of surgical options further ensuring patient safety.Despite a decreasing incidence of toxic megacolon, it remains an interdisciplinary therapeutic challenge.
APA:
Leppkes, M., Ganslmayer, M., Strauss, R., & Neurath, M. (2015). Toxic megacolon. Medizinische Klinik - Intensivmedizin und Notfallmedizin, 110(7), 500-5. https://doi.org/10.1007/s00063-015-0076-1
MLA:
Leppkes, M., et al. "Toxic megacolon." Medizinische Klinik - Intensivmedizin und Notfallmedizin 110.7 (2015): 500-5.
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