Martindale C, Heymans S, Suler A, Antonios P, Dickinson R, Choi J (2017)
Publication Language: English
Publication Type: Journal article, Original article
Publication year: 2017
Book Volume: 64
Pages Range: 1234 - 1244
Journal Issue: 8
DOI: 10.1109/TUFFC.2017.2718513
Ultrasound-driven microbubble (MB) activity is used in therapeutic applications such as blood clot dissolution and targeted drug delivery. The safety and performance of these technologies are linked to the type and distribution of MB activities produced within the targeted area, but controlling and monitoring these activities in vivo and in real time has proven to be difficult. As therapeutic pulses are often milliseconds long, MB monitoring currently requires a separate transducer used in a passive reception mode. Here, we present a simple, inexpensive, integrated setup, in which a focused single-element transducer can perform ultrasound therapy and monitoring simultaneously. MBs were made to flow through a vessel-mimicking tube, placed within the transducer’s focus, and were sonicated with therapeutic pulses (peak rarefactional pressure: 75–827 kPa, pulse lengths:
APA:
Martindale, C., Heymans, S., Suler, A., Antonios, P., Dickinson, R., & Choi, J. (2017). Simultaneous Ultrasound Therapy and Monitoring of Microbubble-Seeded Acoustic Cavitation Using a Single-Element Transducer. IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control, 64(8), 1234 - 1244. https://doi.org/10.1109/TUFFC.2017.2718513
MLA:
Martindale, Christine, et al. "Simultaneous Ultrasound Therapy and Monitoring of Microbubble-Seeded Acoustic Cavitation Using a Single-Element Transducer." IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control 64.8 (2017): 1234 - 1244.
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