The influence of four different anticoagulants on dynamic light scattering of platelets

Raczat T, Kraemer L, Gall C, Weiss DR, Eckstein R, Ringwald J (2014)

Publication Type: Journal article

Publication year: 2014

Journal

Vox Sanguinis Wiley-Blackwell

Publisher: Wiley-Blackwell

Book Volume: 107

Pages Range: 196-9

Journal Issue: 2

DOI: 10.1111/vox.12150

Abstract

For testing of dynamic light scattering of platelets with ThromboLUX (TLX) in platelet-rich plasma (PRP) derived from venous whole blood (vWB), anticoagulation is needed. We compared TLX score in PRPs containing citrate, ethylene-diamine-tetraacetic-acid (EDTA), citrate-phosphate-dextrose-adenine (CPDA) or citrate-theophylline-adenosine-dipyridamole. Initial and late TLX scores were measured after 30-120 min or four to six hours, respectively. Compared with citrate, mean differences in initial TLX score were only significant for CPDA. Also, mean differences between initial and late TLX scores were only significant for CPDA. TLX failed to detect EDTA-induced platelet alterations. The clinical relevance of TLX needs further studies.

Authors with CRIS profile

Tatjana Raczat Medizinische Fakultät Christine Gall Lehrstuhl für Biometrie und Epidemiologie Reinhold Eckstein Department of Transfusion Medicine and Haemostaseology

How to cite

APA:

Raczat, T., Kraemer, L., Gall, C., Weiss, D.R., Eckstein, R., & Ringwald, J. (2014). The influence of four different anticoagulants on dynamic light scattering of platelets. Vox Sanguinis, 107(2), 196-9. https://doi.org/10.1111/vox.12150

MLA:

Raczat, Tatjana, et al. "The influence of four different anticoagulants on dynamic light scattering of platelets." Vox Sanguinis 107.2 (2014): 196-9.

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