Eyelid aging: pathophysiology and clinical management

Damasceno RW, Avgitidou G, Belfort R, Correa Dantas PE, Holbach LM, Heindl LM (2015)

Publication Type: Journal article, Review article

Publication year: 2015

Journal

Arquivos Brasileiros De Oftalmologia Conselho Brasileiro de Oftalmologia

Book Volume: 78

Pages Range: 328-31

Journal Issue: 5

DOI: 10.5935/0004-2749.20150087

Abstract

Life expectancy is increasing in most countries. With increasing age, many individuals may develop involutional ophthalmic diseases, such as eyelid aging. Dermatochalasis, ptosis, ectropion, and entropion are common disorders in middle-aged and older adults. This review outlines the pathophysiology and clinical management of these involutional eyelid disorders. Recently, a decrease in elastic fibers with ultrastructural abnormalities and an overexpression of elastin-degrading enzymes have been demonstrated in involutional ectropion and entropion. This may be the consequence of local ischemia, inflammation, and/or chronic mechanical stress. Eyelid aging with progressive loss of tone and laxity may affect the ocular surface and adnexal tissues, resulting in different clinical symptoms and signs. Surgical management depends on the appropriate correction of the underlying anatomical defect.

Involved external institutions

Universidade Estadual de Ciências da Saúde de Alagoas (UNCISAL)

Brazil (BR) Universität zu Köln

Germany (DE) Federal University of São Paulo / Universidade Federal de São Paulo (UNIFESP)

Brazil (BR) Irmandade da Santa Casa de Misericórdia de São Paulo

Brazil (BR)

How to cite

APA:

Damasceno, R.W., Avgitidou, G., Belfort, R., Correa Dantas, P.E., Holbach, L.M., & Heindl, L.M. (2015). Eyelid aging: pathophysiology and clinical management. Arquivos Brasileiros De Oftalmologia, 78(5), 328-31. https://doi.org/10.5935/0004-2749.20150087

MLA:

Damasceno, Renato Wendell, et al. "Eyelid aging: pathophysiology and clinical management." Arquivos Brasileiros De Oftalmologia 78.5 (2015): 328-31.

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