Vesicles as a model for controlled (de-) adhesion of cells: a thermodynamic approach
Smith AS, Seifert U (2007)
Publication Language: English
Publication Status: Published
Publication Type: Journal article, Review article
Publication year: 2007
Journal
Publisher: ROYAL SOC CHEMISTRY
Book Volume: 3
Pages Range: 275-289
Journal Issue: 3
URI: http://pubs.rsc.org/en/content/articlelanding/2007/sm/b611892e/unauth#!divAbstract
DOI: 10.1039/b611892e
Abstract
We review the specific adhesion between ligand-containing vesicles and receptor-functionalized substrates as an established model system used to study the cell recognition process and its control mechanisms. In order to provide better understanding of the underlying physics and to allow for quantitative exploitation of this system, we develop a simple theoretical framework that accounts for the equilibrium state of adhesion and successfully merges the macroscopic and microscopic aspects of the problem. Several mechanisms that are used to control adhesion or induce de-adhesion are studied on the same level of theory. Specifically, the repelling properties of adhesive molecules, the role of repelling molecules, the action of antagonists for a specific binder as well as the influence of an externally applied force are addressed independently within the same formalism.
Authors with CRIS profile
Involved external institutions
Germany (DE)How to cite
APA:
Smith, A.-S., & Seifert, U. (2007). Vesicles as a model for controlled (de-) adhesion of cells: a thermodynamic approach. Soft Matter, 3(3), 275-289. https://doi.org/10.1039/b611892e
MLA:
Smith, Ana-Suncana, and Udo Seifert. "Vesicles as a model for controlled (de-) adhesion of cells: a thermodynamic approach." Soft Matter 3.3 (2007): 275-289.
BibTeX: Download