Preparation and characterisation of gallium releasing 3-D alginate coated 45S5 Bioglass® based scaffolds for bone tissue engineering

Mourino V, Newby P, Boccaccini AR (2010)

Publication Type: Journal article

Publication year: 2010

Journal

Advanced Engineering Materials Wiley-VCH Verlag

Publisher: Wiley-VCH Verlag

Book Volume: 12

Pages Range: B283-B291

DOI: 10.1002/adem.200980078

Abstract

The aim of this work was to develop functional three-dimensional scaffolds based on Bioglass® derived glass-ceramics for bone tissue engineering (TE) with prophylaxis effect against infections. The highly porous scaffolds were fabricated by the foam replication technique and then coated with sodium alginate crosslinked with Ga3+. It was confirmed that the polymer coating did not affect the interconnectivity of the scaffold pore structure. The resulting composite scaffold exhibited antibacterial effect and improved mechanical properties as well as high bioactivity. The novel Ga3p loaded 45S5 Bioglass1-based scaffolds coated with alginate are promising candidates for bone TE applications. © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Authors with CRIS profile

Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Imperial College London / The Imperial College of Science, Technology and Medicine GB United Kingdom (GB)

How to cite

APA:

Mourino, V., Newby, P., & Boccaccini, A.R. (2010). Preparation and characterisation of gallium releasing 3-D alginate coated 45S5 Bioglass® based scaffolds for bone tissue engineering. Advanced Engineering Materials, 12, B283-B291. https://doi.org/10.1002/adem.200980078

MLA:

Mourino, Viviana, Phillipa Newby, and Aldo R. Boccaccini. "Preparation and characterisation of gallium releasing 3-D alginate coated 45S5 Bioglass® based scaffolds for bone tissue engineering." Advanced Engineering Materials 12 (2010): B283-B291.

BibTeX: Download