Synthesis and Dopamine Receptor Binding of Some Pyrazolo[3',4':6,7]azepino[5,4,3-cd]indoles

Gmeiner P, Hübner H (2003)

Publication Type: Journal article

Publication year: 2003

Journal

Heterocycles Elsevier

Publisher: Elsevier

Book Volume: 60

Pages Range: 1339-1350

Journal Issue: 6

Abstract

A synthesis of some substituted pyrazolo[3′,4′:6,7]azepino[5,4,3-cd]indoles is described and their affinities to dopamine receptors were evaluated. The tested compounds (3a-d and 4a,b) showed micromolar affinity to the bovine D1 receptor subtype and the human D2, D3 and D4 receptor isoforms.

Authors with CRIS profile

Peter Gmeiner Lehrstuhl für Pharmazeutische Chemie Harald Hübner Lehrstuhl für Pharmazeutische Chemie

How to cite

APA:

Gmeiner, P., & Hübner, H. (2003). Synthesis and Dopamine Receptor Binding of Some Pyrazolo[3',4':6,7]azepino[5,4,3-cd]indoles. Heterocycles, 60(6), 1339-1350.

MLA:

Gmeiner, Peter, and Harald Hübner. "Synthesis and Dopamine Receptor Binding of Some Pyrazolo[3',4':6,7]azepino[5,4,3-cd]indoles." Heterocycles 60.6 (2003): 1339-1350.

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