Indoloparacyclophanes: Synthesis and Dopamine Receptor Binding of a Novel Arylbioisostere

Waibel R, Gmeiner P (2001)

Publication Type: Journal article

Publication year: 2001

Journal

Angewandte Chemie International Edition Wiley

Publisher: Wiley-VCH Verlag

Book Volume: 40

Pages Range: 1283-1285

DOI: 10.1002/1521-3757(20010401)113:7<1323::AID-ANGE1323>3.0.CO;2-I

Abstract

Fancy drug candidates: The first preparation of indoloparacyclophanes is reported through the use of the Buchwald variant of the Fischer indole synthesis (see scheme). Receptor binding studies clearly demonstrated that the double-layered molecular scaffold can serve as an effective arylbioisostere.

Authors with CRIS profile

Reiner Waibel Lehrstuhl für Pharmazeutische Chemie Peter Gmeiner Lehrstuhl für Pharmazeutische Chemie

How to cite

APA:

Waibel, R., & Gmeiner, P. (2001). Indoloparacyclophanes: Synthesis and Dopamine Receptor Binding of a Novel Arylbioisostere. Angewandte Chemie International Edition, 40, 1283-1285. https://doi.org/10.1002/1521-3757(20010401)113:7<1323::AID-ANGE1323>3.0.CO;2-I

MLA:

Waibel, Reiner, and Peter Gmeiner. "Indoloparacyclophanes: Synthesis and Dopamine Receptor Binding of a Novel Arylbioisostere." Angewandte Chemie International Edition 40 (2001): 1283-1285.

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