Phenyloxazoles and Phenylthiazoles as Benzamide Bioisosteres: Synthesis and Dopamine Receptor Binding Profiles

Gmeiner P, Einsiedel J, Hübner H (2000)

Publication Type: Journal article

Publication year: 2000

Journal

Bioorganic & Medicinal Chemistry Letters Elsevier

Publisher: Elsevier

Book Volume: 10

Pages Range: 2041-2044

DOI: 10.1016/S0960-894X(00)00405-4

Abstract

Conformationally restricted benzamide bioisosteres were investigated when the aminomethylpyrrolidine derivative 4o proved D3 as well as D4 binding properties which were comparable to those of the atypical neuroleptics sulpiride and clozapine, respectively. (C) 2000 Elsevier Science Ltd.

Authors with CRIS profile

Peter Gmeiner Lehrstuhl für Pharmazeutische Chemie Jürgen Einsiedel Lehrstuhl für Pharmazeutische Chemie Harald Hübner Lehrstuhl für Pharmazeutische Chemie

How to cite

APA:

Gmeiner, P., Einsiedel, J., & Hübner, H. (2000). Phenyloxazoles and Phenylthiazoles as Benzamide Bioisosteres: Synthesis and Dopamine Receptor Binding Profiles. Bioorganic & Medicinal Chemistry Letters, 10, 2041-2044. https://doi.org/10.1016/S0960-894X(00)00405-4

MLA:

Gmeiner, Peter, Jürgen Einsiedel, and Harald Hübner. "Phenyloxazoles and Phenylthiazoles as Benzamide Bioisosteres: Synthesis and Dopamine Receptor Binding Profiles." Bioorganic & Medicinal Chemistry Letters 10 (2000): 2041-2044.

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