Gmeiner P (1998)
Publication Type: Journal article
Publication year: 1998
Publisher: Thieme Publishing / Georg Thieme Verlag
Pages Range: 885-887
Starting from aspartic acid a stereoselective synthesis of enantiomerically pure 4-aminopiperidin-2-ones which can serve as conformationally restrained β-amino acid equivalents in peptidomimetics is described. The synthesis is based on the regioselective functionalization of the 1,4-bis-electrophile 2b and a diastereoselective introduction of various side chain equivalents into the lactam α-position of 4b,c.
APA:
Gmeiner, P. (1998). Homo-Freidinger Lactams: Stereoselective Synthesis of 4-Aminopiperidin-2-one Derivatives from Aspartic Acid. Synlett, 885-887.
MLA:
Gmeiner, Peter. "Homo-Freidinger Lactams: Stereoselective Synthesis of 4-Aminopiperidin-2-one Derivatives from Aspartic Acid." Synlett (1998): 885-887.
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