Löber S, Tschammer N, Hübner H, Melis MR, Argiolas A, Gmeiner P (2009)
Publication Type: Journal article
Publication year: 2009
Publisher: Wiley-VCH Verlag
Book Volume: 4
Pages Range: 325-328
(Graph Presented) Blue makes it happen: The non-uniform charge distribution of the blue colored azulene framework is highly suitable for the bioisosteric replacement of bicyclic heteroarene moieties. Showing an analogous binding mode as heterocyclic dopamine D4 receptor-selective lead compounds, the induction of penile erection in rats over a greater range of doses indicates a putative advantage of the rationally developed azulene derivative 2 b over apomorphine. © 2009 Wiley-VCH Verlag GmbH& Co. KGaA.
APA:
Löber, S., Tschammer, N., Hübner, H., Melis, M.R., Argiolas, A., & Gmeiner, P. (2009). The Azulene Framework as a Novel Arene Bioisostere: Design of Potent Dopamine D4 Receptor Ligands Inducing Penile Erection. ChemMedChem, 4, 325-328. https://doi.org/10.1002/cmdc.200800395
MLA:
Löber, Stefan, et al. "The Azulene Framework as a Novel Arene Bioisostere: Design of Potent Dopamine D4 Receptor Ligands Inducing Penile Erection." ChemMedChem 4 (2009): 325-328.
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